Biomarkers for Parkinson´s Disease with Reflex Tears Correlate with Disease Duration
Objective: To determine if the protein composition of reflex tears differs in Parkinson’s disease (PD) patients stratified by disease duration compared to Healthy Controls (HC).…Non-mercaptalbumin as a potential biomarker of oxidative stress in Parkinson’s and PARK2 disease
Objective: To elucidate the oxidized albumin ratio, which is the redox ratio of human non-mercaptalbumin (HNA) to serum albumin (%HNA), as a biomarker in parkinsonism.…Maladaptive use of LD/CD tablets as painkillers causing Dopamine Dysregulation Syndrome in 4 patients of Advanced Parkinson’s Disease
Objective: To study four cases of maladaptive use of levodopa/carbidopa (LD/CD) as painkillers causing Dopamine dysregulation syndrome (DDS) in Parkinson’s disease (PD) patient in a…Frequency of Impulse Control Disorders and Other Related Behaviors in People with Parkinson’s Disease
Objective: To identify the frequency of impulse control disorders (ICDs) and other related behaviors (i.e. punding, hobbyism, walkabout and dopamine dysregulation syndrome) in people with…Three-year safety and clinical outcomes from the PD-1101 trial of AADC gene therapy for advanced Parkinson’s disease
Objective: To present preliminary 3-year data from the PD-1101 trial of VY-AADC01 for advanced Parkinson’s disease (PD) with motor fluctuations. Background: This 3-year phase 1b…Effects of Rasagiline on Parkinson’s Disease Questionnaire (PDQ-39) Emotional Well-being Domain in Patients with Parkinson’s Disease (PD): A Post-Hoc Analysis of Clinical Trials in Japan
Objective: To evaluate the direct and indirect effects of rasagiline on emotional well-being domain of the PDQ-39 in patients with PD by a post-hoc analysis…Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease: ADAPT-PD Trial: A Prospective Single-Blind, Randomized Crossover, Multi-Center Trial of Deep Brain Stimulation Adaptive Algorithms in Subjects with Parkinson’s Disease
Objective: To demonstrate safety and effectiveness of adaptive deep brain stimulation (aDBS) algorithms in subjects with Parkinson’s disease (PD). Background: DBS is an effective therapy…Serum microRNA expression levels in Turkish patients with Parkinson’s disease
Objective: To determine the serum expression levels of miR-19a, miR-19b, miR-29a, miR-29c, miR-181, miR-195 and miR-221 in Turkish patients with Parkinson's disease (PD) and to…Comparison of gait measures in a clinic and a community setting in people with and without Parkinson’s disease
Objective: This study aimed to investigate measures that best discriminated gait characteristics of people with Parkinson's disease (PD) from age-matched healthy control subjects (HC) in…On-Demand Treatment Preferences of Patients with Parkinson’s Disease and “OFF” Episodes: Heterogeneity Across Patient Subgroups
Objective: To quantify preference heterogeneity for on-demand treatments among patients with Parkinson’s disease (PD) and “OFF” episodes. Background: Patients with PD commonly experience “OFF” episodes.…
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