Opicapone in Clinical Practice in Parkinson’s Disease Patients with Motor Fluctuations: Findings from the OPTIPARK Study
Objective: This real-world study evaluated opicapone (OPC) 50-mg in a heterogeneous population of Parkinson’s disease (PD) patients treated in clinical practice. Background: OPC proved effective…Pill burden reduction in patients with advanced Parkinson’s disease: Comparative effectiveness of carbidopa/levodopa enteral suspension and Deep brain stimulation
Objective: To compare the real-world impact of initiating carbidopa/levodopa enteral suspension (CLES) or deep brain stimulation (DBS) on reducing pill burden (i.e. total number of…Laryngeal movement disorders as a potential clinical biomarker in multiple system atrophy: Results from the LaPD study
Objective: To systematically assess frequency and nature of laryngeal dysfunction in multiples system atrophy (MSA) compared to Parkinson’s disease (PD) and to identify a potential…GCI-induced neurodegeneration and synucleinopathy in non-human primates
Objective: This study aimed at determining the potential to induce MSA pathology in non-human primates. Background: Aggregation of alpha-synuclein has been implicated in several neurodegenerative…Can we stage tau pathology in PSP?
Objective: To evaluate distribution pattern of tau pathology in different PSP clinical subtypes and develop a staging system. Background: Progressive supranuclear palsy (PSP) is a…The effect of comorbid NPH on the clinical feature and progression of Parkinson’s disease
Objective: To analyze the effect of co-existing normal pressure hydrocephalus (NPH) on the clinical course of Parkinson's disease (PD), we examined the disease progression and…Serum neurofilament light chain differentiates early Parkinson’s disease from progressive supranuclear palsy-parkinsonism
Objective: To assess the value of serum neurofilament light chain (NFL) levels in differentiating parkinsonian syndromes. Background: The diagnosis of Parkinson’s disease (PD) mostly relies…Objective Measurement of Muscle Mechanical Properties using a Myometric Device in People with Parkinson’s Disease in a Clinical Setting in Africa
Objective: To examine the feasibility and reliability of using a myometric device to objectively measure mechanical properties of muscles in people with Parkinson’s disease in…Neuropsychiatric non-motor manifestations in patients with focal dystonia
Objective: We aimed to evaluate the neuro-psychiatric manifestations in focal dystonia patients. Background: Idiopathic focal dystonia is one of the most common forms of dystonia…Remotely-monitored home-based physiotherapy is feasible for both people with Parkinson’s disease and physiotherapists
Objective: To investigate the feasibility of a remotely-monitored home-based exercise program for people with Parkinson’s disease (PD) delivered following a centre-based exercise and exercise self-management…
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