MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2020

    Dysphasia as a novel approach for classification of speech disorders in Parkinson’s disease and other forms of neurodegeneration

    E. Vasenina, O. Levin (Moscow, Russian Federation)

    Objective: To classify and identify the features of speech disorders in Parkinson's disease and other neurodegenerative diseases. Background: No unified approach to classification and diagnostics…
  • MDS Virtual Congress 2020

    The interaction of Parkin and TAF15 for the Drosophila in which neuronal defect was induced

    E.J Choi, D.G Lee, CC. Cui, K.Y Kim (Ulsan, Republic of Korea)

    Objective: Our study proposes a novel regulator for the protection of TAF15-induced proteinopathy and adds to our understanding of the exact pathogenic mechanism for TAF15-induced…
  • MDS Virtual Congress 2020

    Pulmonary function in Parkinson’s disease

    A. O'Callaghan, W. Gray, S. Bourke, R. Walker (North Shields, United Kingdom)

    Objective: To establish if pulmonary function is impaired in Parkinson’s disease (PD) and define any pattern of impairment. Background: Parkinson’s disease (PD) is associated with…
  • MDS Virtual Congress 2020

    Impulse Control Disorders and Other Psychiatric Complications in a Series of Patients Treated Levodopa-Carbidopa Instestinal Gel

    A. Contreras, M. Mas, F. Grandas (Madrid, Spain)

    Objective: To determine the frequency of ICDs and other psychiatric complications in a serie of patients of the Movement Disorders Unit of our center, treated…
  • MDS Virtual Congress 2020

    Psychiatric comorbidities in Young Onset Parkinson’s disease

    A. Patwardhan, P. Pal, N. Kamble, R. Yadav (Bangalore, India)

    Objective: The study aims at exploring psychiatric comorbities;namely;anxiety,depression and impulse control disorders(ICD) and their inter relationship in a large cohort of Young onset PD(YOPD)patients. Background:…
  • MDS Virtual Congress 2020

    Population pharmacokinetic analysis of levodopa and carbidopa after subcutaneous administration with and without adjunct oral therapy

    T. Birnberg, G. Smania, M. Bjornsson, N. Jonsson, R. Case, S. Oren, L. Adar, M. Karlsson (Rehovot, Israel)

    Objective: To develop population pharmacokinetic (PK) models for levodopa (LD) and carbidopa (CD) following subcutaneous (SC) infusion, including adjunct oral LD/CD administration. Background: ND0612 is…
  • MDS Virtual Congress 2020

    A Long-Term Safety, Tolerability, and Efficacy Study of Apomorphine Sublingual Film for On-Demand Treatment of “OFF” Episodes in Patients With Parkinson’s Disease: Interim Results

    S. Factor, W. Ondo, S. Isaacson, P. Bhargava, B. Navia (Atlanta, GA, USA)

    Objective: Evaluate the long-term safety (LTS), tolerability, and efficacy of apomorphine sublingual film (APL-130277; APL) for on-demand treatment of “OFF” episodes in patients with Parkinson’s…
  • MDS Virtual Congress 2020

    The exosomal a-syn filaments can be a novel biomarker of Parkinson’s disease

    Y. Ishiguro, T. Tsunemi, A. Yoroisaka, N. Hattori (Tokyo, Japan)

    Objective: This study is aimed to investigate whether the number of exosomes, the amount of total or exosomal a-synuclein (a-syn) filaments in serum can serve as…
  • MDS Virtual Congress 2020

    Pharmacokinetics and Biomarker Changes in NILO-PD, A Phase 2A Study of Nilotinib in Patients with Moderate to Advanced Parkinson’s Disease

    K. Merchant, T. Simuni, B. Fiske, C. Coffey, H. Matthews, R. Wyse, P. Brundin, D. Simon, M. Schwarzschild, D. Weiner, J. Adams, L. Trusso, L. Baker, M. Kostrzebski, T. Ward, G. Rafaloff, C. Venuto (Chicago, IL, USA)

    Objective: To assess serum pharmacokinetics (PK) and cerebrospinal fluid (CSF) concentrations of nilotinib as well as CSF biomarker changes in NILO-PD study. Background: Several cell…
  • MDS Virtual Congress 2020

    Types of Pain in Parkinson`s Disease Patients

    I. Petrov (Skopje, The former Yugoslav Republic of Macedonia)

    Objective: To present the characteristics of four different types of pain in Parkinson`s disease (PD) patients. Background: Neurodegeneration can cause a nociceptive disturbances at many…
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