Are oromotor deficits a late stage signs in Parkinson’s disease?
Objective: To assess any preclinical signs of dysphagia in early PD. Background: Pre-clinical stages of Parkinson’s disease (PD) include the subtle signs of autonomic dysfunction,…Relationship Between a-syn RT-QuIC and a-syn Neuropathologic Burden in Dementia with Lewy Bodies
Objective: To determine if measures of alpha-synuclein (a-syn) real time quaking induced conversion (RT-QuIC) activity are related to a-syn neuropathologic burden in dementia with Lewy…Exploring cognitive aspect of linguistic prosody in Parkinson’s disease
Objective: To explore the correlation between linguistic prosody and cognition in Parkinson's disease Background: Around 90% of patients with Parkinson’s disease (PD) report speech deficit.…Modifiable Comorbidities Associated with Rate of Cognitive Decline in Parkinson’s Disease
Objective: To determine the association between baseline modifiable comorbidities, including cardiovascular disease risk factors, mood disorders, and sleep characteristics, and the rate of change in…Driving in Parkinson’s Disease: A Retrospective Study of Driving and Mobility Assessments
Objective: To describe the characteristics of PD patients assessed at a Driving Mobility Centre and investigate factors that predict driving assessment outcome. Background: To guide…Exploring the role of the retrograde procedural memory in PD in the Luxembourg Parkinson’s Disease Study
Objective: Deepening knowledge of retrograde procedural memory (RPM) in typical Parkinson’s Disease (PD) patients to demonstrate that RPM is impaired in patients with PD. Background:…Disentangling postural instability-gait difficulties classification model for the prediction of cognitive impairment in de novo Parkinson’s Disease patients
Objective: To investigate whether postural instability/gait difficulties (PIGD) phenotype classification or specific PIGD-related MDS-UPDRS items may predict cognitive impairment in de novo Parkinson’s disease (PD)…GWAS on impulse control disorders in Parkinson’s disease
Objective: To identify the genetic factors associated with Impulse control disorders (ICDs) in Parkinson’s disease (PD) patients using a genome-wide approach. Background: ICDs are associated…Rare variants of the LRRK2 gene in the haplotype as one of the potential risk factors for endemic parkinsonism in a small isolated region in the Czech Republic
Objective: The aim of the study was to investigate a co-occurence of rare variants in set of genes frequently associated with parkinsonism. Background: The increased…PARK2 p.Ala82Glu variant is not associated with Parkinson’s disease
Objective: The aim of the study was to analyze potential pathogenicity of the PARK2 p.Ala82Glu mutation, by functional studies of Parkin in the mitophagy paradigm…
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