Cognitive impairment related networks of functional MRI in Parkinson’s disease
Objective: This study attempts to identify cognitive impairment related networks in the subjects with Parkinson’s disease using functional magnetic resonance imaging (MRI). Background: Voxelwise analysis…Identification and clinical characteristics of Mild Cognitive Impairment in Parkinson’s disease
Objective: To examine the characteristics of mild cognitive impairment in Parkinson’s disease (PD) patients with mild cognitive impairment (MCI) Background: Cognitive disturbances in PD detrimentally…The development and application of an adjunct genetic counseling pre-test assessment and video intervention for Parkinson’s disease (PD)
Objective: To develop a method to improve the efficiency of genetic counseling for PD in a multiethnic cohort, with focus on development and assessment of…Significant hypometabolism in the posterior parietal cortex and precuneus in Parkinson’s disease with GBA mutations: [18F]FDG PET study
Objective: We explored [18F]FDG PET findings of PD patients with GBA mutation. Background: Parkinson’s disease (PD) with glucocerebrosidase (GBA) mutations is characterized by early onset…Clinical and genetic profile of Familial Parkinson´s disease in Cali – Colombia
Objective: This study aims to describe the genetic and clinical profile of 32 subjects with familial PD using NGS genetic panel and eMotion software system…H1/H2 MAPT Haplotype and Parkinson’s Disease in an Ashkenazi Jewish Cohort
Objective: To study the Microtubule-Associated Protein Tau (MAPT) H1/H2 haplotype contribution to clinical manifestation of Parkinson’s disease (PD) in an Ashkenazi Jewish (AJ) cohort, focusing…Rotenone exposure is associated with mitochondrial DNA (mtDNA) damage in humans
Objective: To determine if mtDNA damage can serve as a biomarker of prior pesticide exposure. Background: Mitochondrial dysfunction is a hallmark of PD, and exposure…Compartment-specific blockade of dopamine uptake in nigrostriatal pathway reveals role for nigral dopamine function in movement frequency in open-field
Objective: Inhibition of tyrosine hydroxylase activity in the substantia nigra (SN) produces a significant reduction in locomotor motor activity commensurate with decreased dopamine (DA) content…Identifying de novo Parkinson’s disease with optical coherence tomography of the retina: A machine learning classification approach
Objective: To identify and classify de novo Parkinson’s disease patients compared to healthy controls (HC). Background: PD patients experience visual symptoms and retinal degeneration. Studies…Nucleus basalis of Meynert free-water distinguishes and predicts cognitive impairment and longitudinally correlates with cognitive changes in early Parkinson’s disease
Objective: To explore diffusion-based MRI assessments of the nucleus basalis of Meynert (nbM) as a neuroimaging biomarker of cognitive abilities and longitudinal cognitive changes in…
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