MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    The Effects of Telepractice- Based LSVT-BIG Training in Patients with Parkinson’s Disease in Covid-19 pandemic: Preliminary Results

    G. Kaya Aytutuldu, B. Ersoz Huseyinsinoglu, N. Karagoz Sakalli, A. Sen (İstanbul, Turkey)

    Objective: To investigate the effects of telepractice-based LSVT-BIG training on balance and mobility parameters in patients with Parkinson’s Disease (PD). Background: Patients with PD who…
  • MDS Virtual Congress 2021

    Parkinson Progression Marker Initiative – New Science/New Cohorts

    K. Marek, A. Siderowf, T. Simuni, L. Chahine, K. Kieburtz, B. Mollenhauer, D. Galasko, K. Merchant, E. Brown, C. Coffey, R. Dobkin, T. Foroud, K. Poston, E. Flagg, S. Chowdhury, C. Tanner (New Haven, USA)

    Objective: The Parkinson Progression Marker Initiative (PPMI) is expanding its cohorts and exploring additional biomarkers of PD progression to test hypotheses of the underlying molecular…
  • MDS Virtual Congress 2021

    IMPACT OF STANDARD-OF-CARE MEDICATIONS ON TIME-OFF READOUTS IN CLINICAL TRIALS. A QUANTITATIVE SYSTEMS PHARMACOLOGY APPROACH

    R. Rose, E. Mitchell, H. Geerts (Sheffield, United Kingdom)

    Objective: To mitigate clinical variability of Time-Off with various therapeutic combinations Background: There is increasing interest to use wearable-based digital health measures to continuously monitor…
  • MDS Virtual Congress 2021

    Unilateral Subthalamic Versus Unilateral Pallidal Stimulation in Parkinson’s Disease: A Randomized Double-Blind Crossover Study

    ZT. Zeng, LB. Wang, WK. Shi, ZY. Lin, BM. Sun, CC. Zhang, DY. Li (Shanghai, China)

    Objective: To compare the acute effects of deep brain stimulation (DBS) of unilateral subthalamic nucleus (STN) and unilateral globus pallidus interna (GPi) on motor function…
  • MDS Virtual Congress 2021

    The early post-transplant period in Parkinson’s disease: the low intravenous dose effect.

    V. Chyzhyk, V. Ponomarev, N. Aleinikava, A. Boika, M. Zafranskaya, D. Nizheharodava (Minsk, Belarus)

    Objective: To compare the early results of the introduction of MSCs via different routs of administration on the dynamics of the motor symptoms in patients…
  • MDS Virtual Congress 2021

    Global access to Parkinson’s disease treatment

    JLY. Cheong, ZHK. Goh, C. Marras, C. Tanner, M. Kasten, A. Korczyn, L. Chahine, R. Lo, A. Noyce (London, United Kingdom)

    Objective: To examine the availability of PD treatment by country, and analyse differences by national income as defined by the World Bank (high income countries…
  • MDS Virtual Congress 2021

    α-synuclein expression is not mediated by β2-adrenoreceptor modulation in human dopaminergic cells

    M. Langmyhr, IH. Flønes, CC. Cappelletti, C. Tzoulis, M. Toft (Oslo, Norway)

    Objective: Modulation of the β2-adrenoreceptor (also called the β2-adrenergic receptor or β2-adrenoceptor) has been reported to regulate SNCA expression. We sought to determine the expression…
  • MDS Virtual Congress 2021

    Analysis of Amantadine formulations for OFF and Dyskinesia in Parkinson Disease

    W. Oertel, R. Pahwa, R. Hauser, M. Sale, G. Went (Marburg, Germany)

    Objective: Evaluate the effects of amantadine formulations on the treatment of OFF and dyskinesia in Parkinson’s patients. Background: There are currently three formulations of amantadine…
  • MDS Virtual Congress 2021

    Real-world characteristics of advanced Parkinson’s disease patients initiating carbidopa/levodopa enteral suspension

    M. Soileau, I. Malaty, J. Aldred, A. Merola, R. Rodriguez, N. Gupta, I. Sultan, P. Kandukuri, Y. Jalundhwala, O. Ladhani, I. Pan, R. Pahwa (Georgetown, USA)

    Objective: To describe the real-world characteristics of advanced Parkinson’s disease (APD) patients initiating carbidopa/levodopa enteral suspension (CLES) therapy in USA Background: CLES is an FDA…
  • MDS Virtual Congress 2021

    Electroconvulsive therapy for refractory psychiatric symptoms in GBA-related Parkinson disease patient

    JY. Yun, EH. Lee (Seoul, Republic of Korea)

    Objective: This case report aims to highlight the ECT as a promising option on refractory neuropsychiatric manifestations of PD. Background: In GBA-related PD, non-motor symptoms…
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