Evaluation of the QTc prolongation risk of deutetrabenazine
Objective: To assess QTc prolongation risk of deutetrabenazine and its active metabolites by conducting exposure-QTc interval modeling, and to predict QTc prolongation in both CYP2D6…Botulinum Toxin Injections For Movement Disorders During the COVID-19 Pandemic: A Single-Center Experience
Objective: To report on patterns of patients presenting to our center for botulinum toxin injections during the height of the COVID-19 pandemic in New York…A National Data-Linkage Study of Incidence and Prevalence of Primary Dystonia
Objective: To determine the nationwide prevalence and incidence rates of primary dystonia in Wales. Background: The true prevalence and incidence of dystonia remains largely unknown…DNMSQuest: a simple tool for identifying mood disorders in cervical dystonia?
Objective: To compare DNMSQuest scores with validated measures of mood disorder in cervical dystonia patients attending a hospital botulinum toxin clinic. We wished to determine…Sensory Tricks Modulate Corticocortical and Corticomuscular Connectivity in Cervical Dystonia
Objective: To examine mechanisms underlying sensory tricks in cervical dystonia (CD) by examining interactions between cortical areas and between cortical areas and relevant muscles. Background:…Movement Disorder Fellowships: Assessment and Recruitment Strategies to Meet Clinical Needs
Objective: 1. Identify factors leading to lower number of residents interested in movement disorders fellowship. 2. Propose strategies to increase recruitment. Background: The prevalence of…Longitudinal healthcare utilization and costs in Parkinson disease : from pre-diagnosis to 9 years
Objective: The aim of this study was to characterize attributable healthcare utilization and costs in Parkinson disease (PD) in newly diagnosed PD patients managed by…Neuropsychiatric evaluation in patients with functionel movements disorders
Objective: The aim of this study is to investigate the neuropsychiatric evaluations in patients with functional movement disorders. Background: Functional movement disorders include a group…Cognitive profiling in a cohort of Primary Familial Brain Calcification (PFBC) patients
Objective: To investigate neuropsychological and behavioural profile of PFBC patients. Background: PFBC is a rare genetic neurodegenerative disorder characterized by abnormal calcium phosphate deposition basal…Evolving inclusion criteria in early manifest Huntington’s disease (HD) to address striatal atrophy: Lessons from HD-GeneTRX-1, the first gene therapy trial
Objective: To describe the early screening experience and evidence-based adaptations to the inclusion criteria for HD-GeneTRX-1 (NCT04120493). Background: AMT-130 is an AAV5-based gene therapy intended…
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