A Computer-Vision Based Method for Quantifying Parkinsonian Gait
Objective: We proposed and evaluated a novel approach for estimating severity of gait impairment in Parkinson’s disease using a computer vision-based methodology. Background: Gait is…Functional connectivity predictive of efficacy for thalamic deep brain stimulation for Tourette Syndrome
Objective: To investigate whether outcome of thalamic deep brain stimulation (DBS) for Tourette Syndrome can be predicted by functional connectivity estimates seeding from individual stimulation sites.…Are we addressing the emotional burden? – recognition of mood disorders in patients with essential tremor
Objective: To examine the assessment of non-motor symptoms in essential tremor in movement disorder clinics. Background: Essential tremor (ET) is one of the most common…Dysautonomia and cognitive impairment in Essential Tremor: is there a link?
Objective: To investigate the relationship between autonomic dysfunction and cognitive impairment in Essential Tremor (ET). Background: Even though the term ‘essential’ was used to reflect…Towards a better understanding of social work practice in Parkinson’s disease care
Objective: To understand and document the roles and utilization of clinical social workers (SW) in the care of Parkinson’s disease (PD). Background: The importance of an interdisciplinary and evidence-based approach to…Spinocerebellar ataxia (SCA) type 2 and type 8: a tale of two repeat expansions in a single patient
Objective: To describe the rare occurrence of coexisting SCA Types 2 and 8 in a pediatric patient. Background: SCAs are a group of autosomal dominant…Reversible hemichorea due to contralateral anterior cerebral artery territory hypoperfusion
Objective: We report hemichorea due to hypoperfusion of the contralateral anterior cerebral artery (ACA) territory (including caudate nucleus and its connections) that reversed with revascularization.…Pilot study to evaluate pimavanserin for the treatment of motor and behavioral symptoms of Tourette syndrome.
Objective: To determine whether pimavanserin has an effect on motor and behavioral aspects of Tourette syndrome (TS). Background: Pimavanserin is a serotonin 2A receptor inverse…Carboplatin, Paclitaxel, and Nivolumab-induced Parkinsonism Responsive to Levodopa
Objective: To present the first reported case of reversible, levodopa sensitive, chemotherapy- induced parkinsonism due to the combination of carboplatin, paclitaxel, and nivolumab. Background: Many case reports describe antineoplastic agents causing reversible parkinsonism, most commonly, cyclophosphamide, cytosine arabinoside, and cyclosporine. To our knowledge, drug-induced parkinsonism related to combination therapy of paclitaxel, carboplatin, and nivolumab has never been…A Phase 3 Trial Evaluating the Efficacy, Duration of Effect, and Safety of DaxibotulinumtoxinA for Injection in the Treatment of Cervical Dystonia
Objective: To evaluate the efficacy and safety of two doses of DaxibotulinumtoxinA for Injection (DAXI) vs placebo for treatment of cervical dystonia (CD). Background: DAXI…
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