MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Racial and ethnic differences in patients with Parkinson’s Disease across Parkinson’s Disease Centers of Excellence

    D. Di Luca, S. Luo, T. Davis, A. Ramirez-Zamora, M. Rafferty, N. Dahodwala, C. Marras (Toronto, Canada)

    Objective: To investigate treatment, health-related quality of life, and other outcome differences in patients with Parkinson’s Disease (PD) across race and ethnicity. Background: The inclusion…
  • MDS Virtual Congress 2021

    Morbidity and mortality from neurodegenerative patients hospitalized with COVID-19 in the Chicagoland area

    R. Patel, G. Stebbins, B. Barton (Chicago, USA)

    Objective: To assess morbidity and mortality of acute COVID-19 infection in hospitalized patients with neurodegenerative diseases and compare with age-matched controls. Background: Outcomes from COVID-19…
  • MDS Virtual Congress 2021

    Significant increase of new pediatric functional movement disorders during the COVID-19 global pandemic

    K. Mackenzie, J. O'Malley (Palo Alto, USA)

    Objective: This study aims to assess the incidence of pediatric Functional Movement Disorders (FMD) during the COVID-19 global pandemic compared to pre-pandemic baseline. Background: Referrals…
  • MDS Virtual Congress 2021

    Automatic and objective speech analysis in Huntington disease

    J. Adams, E. Dorsey, M. Coffey, M. Pawlik, C. Tarolli, R. Schneider, B. Najafi, H. Zhou, A. Vaziri, H. Nguyen (Rochester, USA)

    Objective: To investigate the use of digital technology to assess speech in people with Huntington disease (HD). Background: Dysarthria is common in Huntington disease and…
  • MDS Virtual Congress 2021

    Fine-grained prediction of Huntington’s disease stage using a meta-model approach

    M. Kohli, S. Gregory, R. Scahill, S. Tabrizi, D. Alexander, P. Wijeratne (London, United Kingdom)

    Objective: We developed a machine learning (ML) framework that facilitates prediction of individual-level Huntington’s disease (HD) stage. The proposed meta-model approach classifies participants according to…
  • MDS Virtual Congress 2021

    Development of the Huntington’s Disease Integrated Staging System (HD-ISS)

    S. Tabrizi, S. Schobel, E. Gantman, A. Mansbach, B. Borowsky, P. Konstantinova, T. Mestre, A. Mullin, J. Panagoulias, K. Romero, C. Ross, S. Sivakumaran, E. Turner, M. Zauderer, J. Long, C. Sampaio (London, United Kingdom)

    Objective: To propose a new HD framework, referred to as the HD-ISS, that comprises an HD biological research definition and evidence-based staging centered on prognostic…
  • MDS Virtual Congress 2021

    Lingual myoclonus associated with brain metastasis located near the primary tongue motor cortex: case report.

    G. Velilla Alonso, J. Soto Alsar, JJ. Rodríguez Irausquin, A. Sánchez Soblechero (Madrid, Spain)

    Objective: To report a case of a patient with lung cancer who developed lingual myoclonus, revealing brain metastases. Background: Lingual myoclonus has been described associated…
  • MDS Virtual Congress 2021

    TREMOR-LYTIC AND PREFRONTO-CORTICAL PROPERTIES OF Nigella sativa OIL IN PHENOL-INDUCED MICE MODELS OF ESSENTIAL TREMOR

    R. Folarin, O. Oyeleye, B. Surajudeen, O. Owoniyi, O. Omotosho, N. Asaye, E. Keshinro (Sagamu, Nigeria)

    Objective: This work assessed the tremor-lytic and prefronto-cortical properties of Nigella sativa oil in phenol-induced mice models of essential tremor. Background: Essential tremor is a…
  • MDS Virtual Congress 2021

    The Development of a Parkinson’s Disease Biomarker Inventory Dashboard

    M. Pauley, K. Merchant, S. Hutten, M. Frasier, M. Lawton, D. Dexter, M. Muller, D. Stephenson (Tucson, USA)

    Objective: There is an urgent need for validated biofluid biomarkers in Parkinson’s disease (PD) drug development. Under the auspices of the Critical Path for Parkinson’s…
  • MDS Virtual Congress 2021

    TNF-α Mediated Neuroinflammation Associated with UPRmt in Kaolin Induced Hydrocephalus Mouse Model

    J. Zhu, M. Lee, Y. Jang, Y. Lee, E. Namgung, W. Chung, C. Seo, E. Oh, J. Heo (Daejeon, Republic of Korea)

    Objective: To identify the association between tumor necrosis factor-α (TNF-α) signaling and mitochondrial unfolded protein responses (UPRmt) against ventricular expansion, we used the kaolin induced…
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