Racial and ethnic differences in patients with Parkinson’s Disease across Parkinson’s Disease Centers of Excellence
Objective: To investigate treatment, health-related quality of life, and other outcome differences in patients with Parkinson’s Disease (PD) across race and ethnicity. Background: The inclusion…Morbidity and mortality from neurodegenerative patients hospitalized with COVID-19 in the Chicagoland area
Objective: To assess morbidity and mortality of acute COVID-19 infection in hospitalized patients with neurodegenerative diseases and compare with age-matched controls. Background: Outcomes from COVID-19…Significant increase of new pediatric functional movement disorders during the COVID-19 global pandemic
Objective: This study aims to assess the incidence of pediatric Functional Movement Disorders (FMD) during the COVID-19 global pandemic compared to pre-pandemic baseline. Background: Referrals…Automatic and objective speech analysis in Huntington disease
Objective: To investigate the use of digital technology to assess speech in people with Huntington disease (HD). Background: Dysarthria is common in Huntington disease and…Fine-grained prediction of Huntington’s disease stage using a meta-model approach
Objective: We developed a machine learning (ML) framework that facilitates prediction of individual-level Huntington’s disease (HD) stage. The proposed meta-model approach classifies participants according to…Development of the Huntington’s Disease Integrated Staging System (HD-ISS)
Objective: To propose a new HD framework, referred to as the HD-ISS, that comprises an HD biological research definition and evidence-based staging centered on prognostic…Lingual myoclonus associated with brain metastasis located near the primary tongue motor cortex: case report.
Objective: To report a case of a patient with lung cancer who developed lingual myoclonus, revealing brain metastases. Background: Lingual myoclonus has been described associated…TREMOR-LYTIC AND PREFRONTO-CORTICAL PROPERTIES OF Nigella sativa OIL IN PHENOL-INDUCED MICE MODELS OF ESSENTIAL TREMOR
Objective: This work assessed the tremor-lytic and prefronto-cortical properties of Nigella sativa oil in phenol-induced mice models of essential tremor. Background: Essential tremor is a…The Development of a Parkinson’s Disease Biomarker Inventory Dashboard
Objective: There is an urgent need for validated biofluid biomarkers in Parkinson’s disease (PD) drug development. Under the auspices of the Critical Path for Parkinson’s…TNF-α Mediated Neuroinflammation Associated with UPRmt in Kaolin Induced Hydrocephalus Mouse Model
Objective: To identify the association between tumor necrosis factor-α (TNF-α) signaling and mitochondrial unfolded protein responses (UPRmt) against ventricular expansion, we used the kaolin induced…