MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Remote assessment of prodromal Parkinson’s disease in a LRRK2 G2019S cohort

    J. Soto, S. Jensen-Roberts, T. Meyers, M. Pawlik, J. Moore, A. Sarkar, R. Wilson, P. Auinger, E. Dorsey, B. Valdovinos, K. Amodeo, S. Sharma, R. Holloway, H. Rowbotham, E. Chanoff, P. Cannon, R. Alcalay, R. Schneider (Rochester, USA)

    Objective: To compare remote application of the Movement Disorder Society (MDS) prodromal Parkinson’s disease (PD) criteria to expert clinical determination of possible parkinsonism in a…
  • MDS Virtual Congress 2021

    Integrated Multi-omics of the Gut Microbiome Reveal 2-Hydroxypyridine as a Novel Molecule Relevant to Parkinson’s Disease Pathogenesis

    V. Aho, JP. Trezzi, C. Jäger, S. Schade, C. Trenkwalder, A. Janzen, U. Heins-Marroquin, C. Linster, G. Gomez Giro, J. Schwamborn, T. Kitami, M. Thomas, K. Schmit, C. Martin-Gallausiaux, M. Buttini, M. Mittelbronn, W. Oertel, B. Mollenhauer, P. Wilmes (Esch-Sur-Alzette, Luxembourg)

    Objective: To search for molecular links between Parkinson’s disease (PD) pathogenesis and gut microbes based on integrated multi-omic analyses of fecal samples from patients with…
  • MDS Virtual Congress 2021

    Gut microbiota and nutritional profiles of Parkinson’s disease patients.

    M. Lubomski, X. Xu, A. Holmes, S. Mueller, J. Yang, C. Sue, R. Davis (St Leonards, Australia)

    Objective: We investigated the gut microbiome (GM) composition in association with various clinical features and nutritional data in a large cross-sectional Australian Parkinson’s disease (PD)…
  • MDS Virtual Congress 2021

    Whole-transcriptome analysis of monocyte-derived macrophages from patients with Parkinson’s disease associated with mutations in the GBA gene

    T. Usenko, A. Panteleeva, K. Basharova, M. Nikolaev, A. Kopytova, A. Bezrukova, K. Senkevich, I. Miliukhina, E. Zakharova, S. Pchelina (Gatchina, Russian Federation)

    Objective: To understand specific molecular features of Parkinson’s disease associated with mutations in the GBA gene (GBA-PD), we analyzed the gene expression profile of peripheral-blood…
  • MDS Virtual Congress 2021

    DO FREEZING OF GAIT AND GAIT AUTOMATICITY IN PARKINSON’S DISEASE SHARE THE SIMILAR NEURAL SUBSTRATE?

    F. de Almeida, C. Ugrinowitsch, M. Nucci, D. Coelho, A. Moreira-Neto, E. Barbosa, L. Teixeira, E. Amaro JR., F. Horak, M. Mancini, C. Silva-Batista (São Paulo, Brazil)

    Objective: To verify if freezing of gait (FOG) in Parkinson’s disease (PD) and gait automaticity share a similar neural substrate. Background: FOG in PD may…
  • MDS Virtual Congress 2021

    Insulin resistance and Parkinson’s disease

    E. Hogg, H. Maghzi, P. Mcelhinney, E. Tan, T. Wu, H. Pomeroy, D. Dey, G. Pagano, M. Tagliati (Los Angeles, USA)

    Objective: To investigate peripheral insulin resistance and cerebral FDG-PET changes in Parkinson’s disease (PD). Background: Glycated hemoglobin levels (HbA1c) is used as a marker of…
  • MDS Virtual Congress 2021

    Sex differences in brain and cognition in de novo PD patients

    J. Oltra, C. Uribe, A. Campabadal, A. Inguanzo, G. Monté-Rubio, M. Marti, Y. Compta, F. Valldeoriola, C. Junque, B. Segura (Barcelona, Spain)

    Objective: We aimed to investigate sex differences in brain atrophy and cognition in PD de novo patients through MRI subcortical volumetry and cortical thickness (CTh).…
  • MDS Virtual Congress 2021

    Constipation in Parkinson’s disease: Clinical and Neurosonographic Study

    R. Soliman, N. Kishk, M. Oraby, A. Alsayyad, M. Abdelsalam, M. Abosrea (Cairo, Egypt)

    Objective: We aimed to study the possible impact of constipation on motor, non-motor, depressive symptoms, cognitive functions and neurosonographic findings in idiopathic Parkinson's disease (PD)…
  • MDS Virtual Congress 2021

    Neurofilament light is related to fractional anisotropy in early Parkinson’s diesease

    T. Welton, Y. Tan, S. Saffari, N. Chia, S. Ng, Z. Lu, A. Yong, X. Choi, D. Heng, YC. Shih, S. Hartono, W. Lee, Z. Xu, K. Tay, WL. Au, EK. Tan, LL. Chan, A. Ng, L. Tan (Singapore, Singapore)

    Objective: We aimed to determine whether plasma NfL reflects changes in brain white matter integrity as measured using fractional anisotropy (FA) in patients with early…
  • MDS Virtual Congress 2021

    LFP spectral features associated with therapy complications in typical and early onset Parkinson’s disease

    E. Belova, U. Semenova, A. Gamaleya, A. Tomskiy, A. Sedov (Moscow, Russian Federation)

    Objective: The aim of this study was to search for potential markers in the subthalamic nucleus activity of parkinsonian patients associated with levodopa-induced dyskinesias in…
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