Effects of levodopa on cognitive functions in Parkinson’s disease
Objective: To assess the dynamics of cognitive functions (CF) under the influence of levodopa in PD patients Background: Our research is devoted to an urgent problem-the…Prognostic Modeling of Parkinson’s Disease Progression Using Early Longitudinal Patterns of Change
Objective: To develop a prognostic model using multiple longitudinal measures to predict temporal clinical progression in early PD. Background: Predicting time to Parkinson’s disease (PD)…Digenic R1441G-LRRK2 and Parkin mutations in Parkinson’s Disease: first clinicopathological case report.
Objective: To report a clinicopathological case of digenic PD with R1441G- LRRK2 and PRKN mutations. Background: Digenic inheritance of R1441G-LRRK2 and PRKN mutation is extremely…Building a Global Parkinson’s Genetics Program (GP2): Clinical Cohorts Integration Working Group
Objective: To recruit Parkinson's Disease (PD) cohorts across the world for the global Parkinson's Genetics Program (GP2, http://gp2.org/), harmonise clinical data across cohorts for joint…Clinical and genetic analysis of psychosis in Parkinson’s disease
Objective: This study aimed to examine the association of seven selected polymorphisms of DRD2, ANKK1, COMT and DAT genes with Parkinson’s disease psychosis (PDP) onset.…Axial Impairment Following Deep Brain Stimulation in Parkinson’s Disease: a Surgicogenomic Approach
Objective: We aimed to identify genetic variants associated with clinical heterogeneity in deep brain stimulation outcome of Parkinson’s Disease patients with an overall objective of…Correlating LRRK2 activation status in peripheral blood to urine BMPs in monogenic and idiopathic Parkinson’s disease
Objective: The greatest unmet need in Parkinson’s disease (PD) are disease-modifying treatments. The discovery of monogenic forms of PD has provided invaluable insights into pathomechanisms…Age-dependent multisystem parkinsonian features in a novel neuromelanin-producing transgenic mouse model
Objective: We aim to characterize the consequences of age-dependent intracellular neuromelanin accumulation in catecholaminergic neuronal populations to understand the relationship between this process and the…Interest of optical coherence tomography in Parkinson’s disease
Objective: To compare optical coherence tomography (OCT) results of retinal thickness (RT) and retinal nerve fiber layer (RNFLT) thickness of patients with idiopathic Parkinson's disease…Impaired interhemispheric synchrony in Parkinson’s disease patients with impulse control disorders
Objective: Our objective was to probe the significant role of lateralization in the pathogenesis of ICD. Background: Impulse control disorders (ICD) in Parkinson’s disease (PD) might…
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