MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Effects of levodopa on cognitive functions in Parkinson’s disease

    S. Ismailova, S. Prokopenko (Krasnoyarsk, Russian Federation)

    Objective: To assess the dynamics of cognitive functions (CF) under the influence of levodopa in PD patients Background: Our research is devoted to an urgent problem-the…
  • MDS Virtual Congress 2021

    Prognostic Modeling of Parkinson’s Disease Progression Using Early Longitudinal Patterns of Change

    X. Ren, J. Lin, G. Stebbins, C. Goetz, S. Luo (Foster City, CA, USA)

    Objective: To develop a prognostic model using multiple longitudinal measures to predict temporal clinical progression in early PD. Background: Predicting time to Parkinson’s disease (PD)…
  • MDS Virtual Congress 2021

    Digenic R1441G-LRRK2 and Parkin mutations in Parkinson’s Disease: first clinicopathological case report.

    D. Campo-Caballero, A. Vinagre-Aragón, JF. Martí-Massó, A. Bergareche, A. Gorostidi, R. Ruiz-Onandi, J. Rodríguez-Antigüedad, J. Equiza, P. Iruzubieta-Agudo, I. Albajar, N. Sulibarria, J. Ruiz-Martinez (San Sebastián, Spain)

    Objective: To report a clinicopathological case of digenic PD with R1441G- LRRK2 and PRKN mutations. Background: Digenic inheritance of R1441G-LRRK2 and PRKN mutation is extremely…
  • MDS Virtual Congress 2021

    Building a Global Parkinson’s Genetics Program (GP2): Clinical Cohorts Integration Working Group

    J. Joubert, M. Tan, T. Antar, A. Martinez-Carrasco, H. Iwaki, H. Morris, GP2. Genetics Program (London, United Kingdom)

    Objective: To recruit Parkinson's Disease (PD) cohorts across the world for the global Parkinson's Genetics Program (GP2, http://gp2.org/), harmonise clinical data across cohorts for joint…
  • MDS Virtual Congress 2021

    Clinical and genetic analysis of psychosis in Parkinson’s disease

    B. Radojević, N. Dragašević, A. Milovanović, V. Dobričić, M. Svetel, I. Petrović, M. Savić, I. Jančić, D. Stanisavljević, A. Marjanović, M. Branković, V. Kostić (Belgrade, Serbia)

    Objective: This study aimed to examine the association of seven selected polymorphisms of DRD2, ANKK1, COMT and DAT genes with Parkinson’s disease psychosis (PDP) onset.…
  • MDS Virtual Congress 2021

    Axial Impairment Following Deep Brain Stimulation in Parkinson’s Disease: a Surgicogenomic Approach

    N. Visanji, M. Ghani, E. Yu, E. Kakhki, C. Sato, D. Moreno, T. Naranian, YY. Poon, M. Abdollahi, M. Naghibzadeh, R. Rajalingam, A. Lozano, S. Kalia, M. Hodaie, M. Cohn, M. Statucka, A. Boutet, G. Elias, J. Germann, R. Munhoz, A. Lang, Z. Gan-Or, E. Rogaeva, A. Fasano (Toronto, Canada)

    Objective: We aimed to identify genetic variants associated with clinical heterogeneity in deep brain stimulation outcome of Parkinson’s Disease patients with an overall objective of…
  • MDS Virtual Congress 2021

    Correlating LRRK2 activation status in peripheral blood to urine BMPs in monogenic and idiopathic Parkinson’s disease

    S. Gomes, A. Garrido, F. Tonelli, E. Tolosa, M. Marti, D. Anderson, N. Pratuseviciute, F. Hsieh, T. Bruecke, T. Koenig, C. Hotzy, J. Ruiz-Martínez, A. Bergareche-Yarza, E. Mondragón Rezola, A. Vinagre Aragón, I. Croitoru, A. Gorostidi Pagola, L. Paternain Markinez, F. Valldeoriola, K. Merchant, S. Padmanabhan, A. Zimprich, D. Alessi, E. Sammler (Dundee, United Kingdom)

    Objective: The greatest unmet need in Parkinson’s disease (PD) are disease-modifying treatments. The discovery of monogenic forms of PD has provided invaluable insights into pathomechanisms…
  • MDS Virtual Congress 2021

    Age-dependent multisystem parkinsonian features in a novel neuromelanin-producing transgenic mouse model

    N. Peñuelas, A. Laguna, M. Gonzalez-Sepulveda, LL. Miquel-Rio, N. Benseny-Cases, H. Xicoy, J. Compte, A. Nicolau, M. Lorente-Picón, E. álvarez-Marimon, J. Romero-Giménez, A. Parent, T. Cuadros, F. Cacho-Nerin, J. Cladera, A. Bortolozzi, I. Carballo-Carbajal, M. Vila (Barcelona, Spain)

    Objective: We aim to characterize the consequences of age-dependent intracellular neuromelanin accumulation in catecholaminergic neuronal populations to understand the relationship between this process and the…
  • MDS Virtual Congress 2021

    Interest of optical coherence tomography in Parkinson’s disease

    N. Chtaou, S. Bouchal, A. El Midaoui, Z. Souirti, M F. Belahsen, M. Bouhlal (Fez, Morocco)

    Objective: To compare optical coherence tomography (OCT) results of retinal thickness (RT) and retinal nerve fiber layer (RNFLT) thickness of patients with idiopathic Parkinson's disease…
  • MDS Virtual Congress 2021

    Impaired interhemispheric synchrony in Parkinson’s disease patients with impulse control disorders

    C. Gan, K. Zhang, Y. Yuan (Nanjing, China)

    Objective: Our objective was to probe the significant role of lateralization in the pathogenesis of ICD. Background: Impulse control disorders (ICD) in Parkinson’s disease (PD) might…
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