α-synuclein expression is not mediated by β2-adrenoreceptor modulation in human dopaminergic cells
Objective: Modulation of the β2-adrenoreceptor (also called the β2-adrenergic receptor or β2-adrenoceptor) has been reported to regulate SNCA expression. We sought to determine the expression…Analysis of Amantadine formulations for OFF and Dyskinesia in Parkinson Disease
Objective: Evaluate the effects of amantadine formulations on the treatment of OFF and dyskinesia in Parkinson’s patients. Background: There are currently three formulations of amantadine…Real-world characteristics of advanced Parkinson’s disease patients initiating carbidopa/levodopa enteral suspension
Objective: To describe the real-world characteristics of advanced Parkinson’s disease (APD) patients initiating carbidopa/levodopa enteral suspension (CLES) therapy in USA Background: CLES is an FDA…Electroconvulsive therapy for refractory psychiatric symptoms in GBA-related Parkinson disease patient
Objective: This case report aims to highlight the ECT as a promising option on refractory neuropsychiatric manifestations of PD. Background: In GBA-related PD, non-motor symptoms…Natural History of Probable MSA in India: A Prospective Cohort Study
Objective: We aimed to prospectively study the natural history of probable multiple system atrophy (MSA) including autonomic testing, survival analysis; and assess whether serum alpha-synuclein…Backward Fall Protection Garment for patients of PSP and other Parkinsonian Syndromes.
Objective: To create a sensor controlled wearable system with an inflatable collar that offers protection against head, spine and shoulder girdle injuries in case of…To Prescribe or Not to Prescribe: The impact of Parkinson’s nurse prescribers
Objective: After formal training, Parkinson’s Nurse Specialists (PNS) can act as independent and supplementary prescribers and initiate/titrate medication. This paper will discuss the impact of…Early-onset vs. Late-onset Parkinson’s disease
Objective: To determine the clinical and therapeutic peculiarities that distinguish Early onset Parkinson’s disease (EOPD) from late onset Parkinson’s disease (LOPD). Background: Age is the…Challenges in Implementing Relevant Exercise Interventions in Mouse Models of Parkinson’s Disease
Objective: To determine the suitability of a motorized wheel as a forced exercise modality that does not rely on aversive stimuli for use in Parkinson’s…Perampanel inhibits α-synuclein transmission in Parkinson’s disease models
Objective: To examine the effect of perampanel, an antiepileptic drug, on α-synuclein transmission in cultured cells and mouse models of Parkinson’s disease. Background: The intercellular transmission of pathogenic proteins…
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