Causes of deaths in patients with Parkinson’s disease in the era before the use of modern drug therapy and at the present time
Objective: to study the impact of modern pharmacotherapy of Parkinson's disease (PD) on the main causes of death. Background: the modern era of the use…The responsiveness of arm swing to dopaminergic medication in Parkinson’s disease depends on task complexity
Objective: The aim of this study is to analyse the responsiveness of arm swing during walking to dopaminergic medication in patients with Parkinson’s disease. Background:…Mapping regional alpha-synuclein seeding capacity in Multiple System Atrophy
Objective: The objective of our work was to develop a novel high-throughput cell-free assay that allowed us to perform a comprehensive characterization of α-synuclein seeding…Early detection of change in motor and cognitive symptoms in a longitudinal Progressive Supranuclear Palsy cohort – the OxQUIP study.
Objective: We aimed to determine longitudinal changes in motor and cognitive features of Progressive Supranuclear Palsy using multiple closely spaced follow-up timepoints over a period…Hemiparkinsonism Due to Diencephalic Lesion with 24 Years of Levodopa Response and Only Mild Dyskinesia
Objective: To present a case of a long-standing hemiparkinsonism due to cerebral lesion with a continuous response to a stable dose of levodopa with only…How Covid-19 would affect parkinsonism patients’ mortality
Objective: To investigate the prevalence and mortality of Covid-19 among parkinsonism patients in addition to worsening of motor symptoms of these patients. Background: Parkinsonism can…Association between Alzheimer’s disease co-pathology and neuropsychiatric symptoms in Lewy body dementia
Objective: To identify the associations between Alzheimer Disease (AD) co-pathology and neuropsychiatric symptoms in Lewy body dementia (LBD). Background: Dementia with Lewy Bodies (DLB) and…Elucidating multimodal endophenotypes of APOE-ε4 in α-synucleinopathies
Objective: To systematically identify phenotypes that consistently associate with the ε4-allele of apolipoprotein E (APOE-ε4) in α-synucleinopathies. Background: The APOE-ε4 presents an elevated risk not…Baseline cognitive profile is closely associated with long-term motor prognosis in newly diagnosed Parkinson’s disease
Objective: To investigate the association between cognitive function at baseline and the progression of motor disability in Parkinson’s disease (PD). Background: There is increasing clinical…The volume of STN tissue activated by DBS and the strength of its structural connectivity with SMA predicts the effects of STN-DBS on response inhibition
Objective: To test the hypothesis that antidromic activation of the hyperdirect pathway might mediate the effects of STN-DBS on movement initiation control. Background: In PD,…
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