Longitudinal changes in nigral neuromelanin in early, levodopa-treated Parkinson’s disease
Objective: To assess longitudinal changes in neuromelanin (NM) content in the substantia nigra compacta (SNc) and its lateral-ventral subregion in Parkinson’s disease (PD). Background: NM-sensitive…DAT-SPECT in old onset Parkinson’s disease: should we trust?
Objective: . Background: Scans without evidence of dopaminergic deficit (SWEDD) refers to patients clinically diagnosed with Parkinson’s disease (PD), but show normal findings on dopamine…Progression of nigrostriatal dysfunction in Parkinson’s disease: a longitudinal multimodal PET study
Objective: To investigate the longitudinal course of nigrostriatal metabolic and dopaminergic dysfunction and its impact on symptom severity in Parkinson's disease (PD) patients using a…Longitudinal Study of Grey Matter Nuclei in Early Parkinson’s Disease using Diffusion Kurtosis Imaging
Objective: We aimed to determine whether microstructural characteristics of key grey matter nuclei would be differentially altered between baseline and two-year timepoints in Parkinson’s disease…Emotional stress exacerbates parkinsonian resting tremor
Objective: To examine the role emotions may play in modulating the characteristics of parkinsonian resting tremor. Background: There is ample evidence showing cognitive stress can…Influence of Levodopa on Archimedes Spiral Drawings in Idiopathic Parkinson’s Disease
Objective: To study the effects of levodopa on Archimedes spiral drawings by idiopathic Parkinson’s Disease (PD) patients. Background: Handwriting difficulty can develop as an early…Lateralization of cochlear dysfunction as a specific biomarker of Parkinson’s disease; role for cholinergic transmission?
Objective: To understand to what extent an early cochlear dysfunction may represent an additional non-motor signature of Parkinson’s disease (PD) patients. Further, whether it may…Olfactory dysfunction in incidental Lewy body disease and Parkinson’s disease: An update
Objective: Using a larger sample size compared to our previous study, we evaluated the relationship between olfactory dysfunction based on the University of Pennsylvania Smell…Implementing Systematic Screening and a Treatment Algorithm for Depression in Parkinson’s Disease
Objective: Assess the feasibility and impact of systematic depression screening and management in movement disorders centers. Background: Depression is common in Parkinson’s disease (PD) and…Functional Constipation in Parkinson’s Disease
Objective: To analyze and compare the Rome IV Criteria of Functional Constipation between PD and HC, with that followed by MDS-NMS, intended for determining clinical…
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