MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • MDS Virtual Congress 2021

    Is cognitive performance related to motor performance among people with Parkinson disease?

    K. Rawson, L. Tueth, T. Baker, J. Cavanaugh, C. Colon-Semenza, T. Deangelis, D. Fulford, T. Nordahl, C. Thomas, M. Lavalley, M. Saint-Hilaire, J. Zajac, T. Ellis, G. Earhart (St. Louis, USA)

    Objective: To examine the relationship between cognitive and motor functioning among people with Parkinson disease (PD). Background: PD is a disabling, chronic condition affecting both…
  • MDS Virtual Congress 2021

    EIF4G1 gene variants in a family affected by Parkinson´s disease

    C. Borrue (San Sebastián Reyes, Spain)

    Objective: Describe a novel mutation on a family affected by  Parkinson´s disease. Background: 46 years old woman. She came  to hospital complaining about  tremor and…
  • MDS Virtual Congress 2021

    α-Synuclein in sympathetic nerve fibers distinguishes PRKN from LRRK2 and other genetic forms of Parkinson’s Disease

    R. Isonaka, D. Goldstein, W. Zhu, E. Yoon, D. Ehrlich, A. Schindler, A. Kokkinis, M. Sabir, S. Scholz, S. Bandres-Ciga, C. Blauwendraat, P. Gonzalez-Alegre, G. Lopez, E. Sidransky, D. Narendra (Bethesda, USA)

    Objective: This cross-sectional observational study compared magnitudes of intra-neuronal deposition of α-synuclein in common and rare genetic forms of Parkinson’s disease. Background: Cytoplasmic inclusions of…
  • MDS Virtual Congress 2021

    Blood-based circulating microRNAs for discriminating between Parkinson’s disease subtypes

    MT. Periñán, P. Gómez-Garre, S. Jesús, D. Buiza-Rueda, MV. Jimenez-Jaraba, D. Macías-García, AD. Adarmes-Gómez, P. Mir (Seville, Spain)

    Objective: The aim of this study was to establish candidate blood miRNAs biomarkers for PD by comparing differences in miRNAs expression between distinct PD subtypes. Background: Blood…
  • MDS Virtual Congress 2021

    LIPAD (LRRK2/Luebeck) International Parkinson’s Disease Study: Protocol and feasibility study

    T. Usnich, EJ. Vollstedt, N. Schell, V. Skrahina, X. Bogdanovic, H. Gaber, T. Förster, A. Heuer, N. Koleva-Alazeh, I. Csoti, A. Nazli Basak, S. Ertan, G. Genc, P. Bauer, K. Lohmann, A. Grünewald, E. Schymanski, J. Trinh, S. Schaake, D. Berg, D. Gruber, S. Isaacson, A. Kühn, B. Mollenhauer, D. Pedrosa, K. Reetz, E. Sammler, EM. Valente, F. Valzania, J. Volkmann, S. Zittel, N. Brüggemann, M. Kasten, A. Rolfs, C. Klein (Lübeck, Germany)

    Objective: To systematically assess clinical signs and symptoms including non-motor features, comorbidities, medication and environmental factors in 1,000 participants internationally: 300 with LRRK2 (Leucine-rich repeat…
  • MDS Virtual Congress 2021

    Fatty acids and Glucocerebrosidase activity as potential biomarkers of stearyl-CoA desaturase inhibition; an observational study of inter and intraday variation in healthy volunteers and patients with Parkinson’s disease

    P. Eijsvogel, A. Gorbenko, D. Tardiff, M. Skupien, M. de Kam, P. Kremer, E. van Brummelen, B. Robertson, GJ. Groeneveld (Leiden, Netherlands)

    Objective: This study aimed to assess the naturally occurring levels and variation in plasma fatty acids (FA) and ceramide metabolism in healthy volunteers (HV) and…
  • MDS Virtual Congress 2021

    PD phenotype with premotor RBD is associated with a dysbiotic profile of gut microbiota.

    V. Oppo, S. Vascellari, M. Melis, A. Manzin, G. Cossu (Cagliari, Italy)

    Objective: The aim of the study was to compare the fecal microbial composition of a group of PD patients with and without premotor RBD. Background:…
  • MDS Virtual Congress 2021

    Longitudinal change in thalamic white matter macrostructure and volume in Parkinson’s disease depression

    R. Bhome, A. Zarkali, J. Cole, R. Weil (London, United Kingdom)

    Objective: To investigate thalamic subnuclei volume and macrostructural white matter changes in Parkinson’s disease (PD) depression. Background: Depression is the most common neuropsychiatric feature of…
  • MDS Virtual Congress 2021

    Dynamic functional connectivity changes in Parkinson’s disease patients with REM sleep behavior disorder

    C. Gan, K. Zhang, Y. Yuan (Nanjing, China)

    Objective: Our aim was to explore dynamic network connection changes in PD patients with RBD. Background: Rapid eye movement (REM) sleep behavior disorder (RBD) is…
  • MDS Virtual Congress 2021

    Association of presynaptic dopaminergic denervation with therapeutic effects of globus pallidus deep brain stimulation on freezing of gait in advanced Parkinson’s disease

    SH. Lee, MS. Kim, YS. Hwang, SY. Jo, SR. Jeon, SJ. Chung (Seoul, Republic of Korea)

    Objective: To investigate the association of presynaptic dopaminergic denervation with the therapeutic effect of globus pallidus (GPi) DBS in advanced PD patients with FOG. Background:…
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