Month 24 results of a virtual longitudinal, observational study of Parkinson’s disease: The AT-HOME PD cohort
Objective: To describe the change in characteristics of Parkinson’s disease (PD) clinical trial participants over 24 months following trial participation in a remote, longitudinal observational…A case with clinical features of alpha-synuclein- and tauopathy: Genetic and histopathological workup.
Objective: Here, we present a clinical case that mimicked the coincidence of idiopathic Parkinson’s disease (PD) and tauopathy. Background: Mutation in leucine-rich-repeat-kinase 2 (LRRK2) gene…Programming algorithm for the management of speech impairment in STN-DBS for Parkinson’s disease
Objective: To establish an evidence- and experience-based algorithm for the management of speech impairment (SI) in Parkinson’s disease (PD) patients treated with STN-DBS. Background: STN-DBS…Nigral microvasculature imaging in Parkinson’s disease
Objective: The goal of this work is to image the microvasculature of the midbrain, in particular the substantia nigra in Parkinson’s disease (PD) patients using…Exploratory delayed-start analysis of PASADENA evaluating the efficacy of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease
Objective: To evaluate the effect of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease (PD) using an exploratory delayed-start analysis of Part…Paroxysmal Musician’s Dyskinesia
Objective: To report a case of tics associated with paroxysmal kinesigenic dyskinesia in a patient with PRRT2 mutation. Background: Paroxysmal kinesigenic dyskinesia (PKD) is characterized…History of Comorbidities and their Association with Developing Cognitive Dysfunction in PD
Objective: To examine comorbidities associated with incident cognitive dysfunction in PD. Background: The risk of dementia is up to six-times higher in PD compared to…Utilisation of the Clinical Frailty Scale to prompt transfer of patients with Parkinson’s disease from Neurology to Geriatric Medicine services.
Objective: The aim of this study was to determine the feasibility of the Clinical Frailty Scale (CFS) as a tool to trigger clinicians' transfer of…Eye closure during tasks in blepharospasm (BSP)
Objective: To quantify modulation of eye closure rates during activities of daily living in individuals with BSP and asymptomatic individuals with and without family history…Measuring functional cognition with the Short Weekly Calendar Planning Activity in patients with Parkinson’s disease and non-manifesting LRRK2 and GBA carriers
Objective: The aims of this study were to explore the feasibility of the short Weekly Calendar Planning Activity (WCPA-10) to investigate functional cognition in patients…
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