C-SURF: DBS programming using probabilistic maps as an efficient new approach to treat patients with dystonia: the results of a feasibility study.
Objective: To evaluate the clinical potential of a novel computer-guided prediction of optimal stimulation settings for pallidal DBS for the treatment of motor symptoms of…Automated scoring of REM sleep without atonia using the open-source software RBDtector
Objective: To facilitate quantification of REM sleep without atonia (RSWA) and thereby identify patients with rapid eye movement (REM) sleep behaviour disorder (RBD). Background: RBD…Addressing pathological alpha-synuclein aggregation using a small molecule strategy
Objective: The discovery of cell-permeable, orally bioavailable and brain penetrant small molecules with the potential of inhibiting aggregation and intracellular accumulation of pathological alpha-synuclein (a-syn)…Can we add whey protein supplementation in patients with Parkinson’s disease without interfering with levodopa response?
Objective: The main endpoint of the study was to evaluate if a daily intake of whey protein-based dietary supplement causes a worse response to levodopa…NIMHANS Neuropsychological Battery for Elderly in Parkinson’s disease patients: Validation and diagnosis using MDS PD-MCI task force criteria in Indian population
Objective: To validate NIMHANS Neuropsychological Battery for Elderly( NNB-E) and evaluate cognitive impairment in Parkinson's disease (PD) patients in comparison with healthy controls. Background: Cognitive…Hyperkinetic movement disorder following Covid: A Temporal corelation or Coincidental ?
Objective: Hypokinetic movement disorder and parkinsonian like picture has been well described in literature but hyperkinetic movements are extremely rare and less highlighted in global…The anti-alpha-synuclein antibody Lu AF82422 binds to pathological alpha-synuclein species from human brains and inhibits seeded alpha-synuclein aggregation
Objective: Lu AF82422 is a human IgG1 monoclonal antibody that binds all known forms of alpha-synuclein (aSyn), including monomeric, aggregated and truncated. Data are presented…Noninvasive focal delivery of Adeno Associated Vectors (AAV) with magnetic resonance-guided focused ultrasound in non-human primates
Objective: Focal brain delivery of gene therapy in non-human primates is a major step towards the translation of this technology for use in humans. We…Cannabinoids for painful dystonia in corticobasal syndrome: a report of three patients
Objective: We aimed to assess the efficacy of cannabinoids in painful dystonia of corticobasal syndrome (CBS) patients Background: The clinical phenotype of CBS includes limb…Network Fingerprint of Stimulation-Induced Speech Impairment in Parkinson’s Disease
Objective: To explore structural network correlates of stimulation-induced dysarthria (SID) in patients with Parkinson’s Disease (PD) chronically treated with deep brain stimulation (DBS) of the…
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