Within patient comparison of neurostimulator longevity; sequentially contrasting the Medtronic Activa PC to the Medtronic Percept PC utilizing in-device battery estimates
Objective: To examine the differences between Actual Activa PC longevity and the estimated longevity of the Percept PC, utilizing identical contact configurations and programming parameters.…Retinal vascular change of Parkinson’s disease patients with orthostatic hypotension
Objective: In the present study, we investigated difference of microvasculature of Parkinson’s disease (PD) patients with orthostatic hypotension (OH) and without OH, using optical coherence…Machine learning algorithms for classification and analysis of pen-on-paper Archimedes spirals
Objective: To classify tremor syndromes from freely hand drawn pen-on-paper Archimedes spirals using classical machine learning techniques. Background: Spiral drawings (Archimedean) are commonly used in…CCL5 promotes Th17 migrating into SNpc by promoting Th17 proportion increase and LFA-1 expression
Objective: To explore the specific pathway by which CCL5 induces Th17 cells migrating into substantia nigra pars compacta (SNpc) to aggravate Parkinson's disease (PD). Background:…Inflammatory microglial and astroglial phenotype associated with pathological alpha-synuclein inclusions in the substantia nigra
Objective: To characterize neuroinflammatory gene expression in microglia and astrocytes associated with early alpha-synuclein (a-syn) inclusion formation. Background: Parkinson’s disease (PD) is characterized by alpha-synuclein…Impact of istradefylline on the adjustment of levodopa dose escalation in Parkinson’s disease: Results of the ISTRA ADJUST PD randomized, controlled study
Objective: To evaluate the effect of istradefylline (IST), an adenosine A2A receptor antagonist, on the adjustment of levodopa dose escalation in patients with Parkinson’s disease…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.