Chikungunya: An emerging arthropod borne disease presenting as rhombencephalitis with near complete recovery
Objective: To report the clinical course and good neurological outcome of severe Chikungunya rhombencephalitis. Background: Chikungunya is an emerging Aedes mosquito borne virus that is…Gerstmann-Straussler-Scheinker Syndrome Manifesting Levodopa-Responsive Parkinsonism, Levodopa-Induced Dyskinesia, and Abnormal DaT-SPECT
Objective: The objective of this report is to describe previously unreported features in a patient with Gerstmann-Straussler-Scheinker syndrome (GSS) due to the F198S mutation. Background:…Dorsolateral nigral hyperintensity on 1.5 versus 3T susceptibility-weighted magnetic resonance imaging in neurodegenerative parkinsonism
Objective: In contrast to their 1.5T counterparts, high field MRI scanners are often unavailable in clinical routine, particularly in primary care facilities and underserved regions.…Impact on non-motor symptoms, cognition, and QoL after 1-year of DBS for Parkinson’s Disease: An interim report from the ADROIT NAPA sub-study
Objective: To present the impact on cognition, quality of life, and non-motor symptoms after 1-year of DBS for Parkinson’s Disease through the ADROIT post-market study.…Paliperidone induced neuroleptic malignant syndrome treated with electroconvulsive therapy and continuous apomorphine: A case report
Objective: Neuroleptic malignant syndrome (NMS) is a neurological emergency that is often induced by antipsychotic drugs. NMS may be mortal if left untreated. Background: In…Silencing dopamine neurons during sleep slows disease progression in parkinsonian mice
Objective: To develop a treatment to stop or slow the progression of Parkinson's disease. Background: Parkinson’s disease (PD) is believed to be caused by the…Neuroanatomical underpinnings of apathy in Parkinson’s Disease
Objective: To investigated the integrity of white matter tracts within basal ganglia-frontal networks in PD patients with and without apathy, and relate these to specific…The mGlu2 positive allosteric modulator BINA extends enhances low dose L-DOPA anti-parkinsonian action in the MPTP-lesioned marmoset
Objective: To determine the effect of positive allosteric modulation of the metabotropic glutamate type 2 (mGlu2) receptor in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset using a low…Botulinum Toxin Therapy for Medication and DBS Refractory Foot Dystonia of Parkinsonism
Objective: To determine efficacy and safety of BTX therapy in patients with medically refractory foot dystonia secondary to Parkinson’s disease (PD) or atypical Parkinsonism (AP)…A Patient-Centered Outcomes Survey in Parkinson’s Disease: Results of Cognitive Pre-Testing
Objective: To validate the Rush Parkinson's Disease Patient-Centered Outcomes Questionnaire (RUSH-PCO-Q). Background: The RUSH-PCO-Q aims to address the lack of patient-centered outcomes in the field…
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