Hemichorea secondary to Middle Cerebral Artery (MCA) Stenosis without evidence of ischemic stroke in the basal ganglia
Objective: To describe two patients who presented with hemichorea from isolated MCA stenosis without evidence of basal ganglia stroke. Background: Hyperkinetic movement disorders can occur…Response of freezing, posture and voice to increasing levodopa doses in Parkinson’s disease
Objective: To analyze the resistance to high levodopa doses of FoG, posture, speech, and gait features in PD patients during a daily-ON therapeutic condition. Background:…Theta-burst Cycling for Deep Brain Stimulation
Objective: To test the clinical efficacy of rapid-cycling deep brain stimulation (DBS) in children and young adults with dystonia. Background: Cycling of DBS for variable…Cognitive-motor tests markedly increase the diagnostic rate of “On-meds” freezing of gait in Parkinson’s disease during clinical visits
Objective: To develop a testing and recording system that can reliably increase the rate of diagnosing freezing of gait (FOG) in patients living with Parkinson’s…Subcortical Atrophy and Fall Risk in Parkinson’s Disease
Objective: To evaluate the relationship between various measures of subcortical atrophy with fall risk in PD. Background: Falls occur in nearly 70% of people with…CAREGIVERS BURDEN IN CARING FOR PERSONS WITH PARKINSON’S DISEASE: A SURVEY FROM A TEACHING HOSPITAL IN GHANA
Objective: To determine the burden of caregivers in caring for persons with Parkinson’s disease (PD) and establish the relationship between the burden of care and…Utility of Seed Amplification Assay for Detecting α-synuclein in Formalin-Fixed Paraffin Embedded Skin Samples in Parkinson’s Disease
Objective: To determine the sensitivity for Parkinson’s disease (PD) diagnosis of seed amplification assay (SAA) for α-synuclein (α-syn) in formalin-fixed paraffin-embedded (FFPE) skin specimens and…Preclinical Characterization of Suvecaltamide for Essential Tremor
Objective: To characterize the in vitro T-type calcium (CaV3) channel target pharmacology and in vivo anti-tremor profile of suvecaltamide (JZP385, CX-8998). Background: CaV3 channels, a…The level of glial neurotrophic factor in blood plasma depending on the stage of Parkinson’s disease
Objective: To study the level of glial neurotrophic disease in blood plasma in patients with Parkinson's disease (PD) depending on the stage Background: Parkinson's disease…Investigation of Modifiers of β-Glucocerebrosidase in Cell Models of Parkinson’s Disease
Objective: We firstly aim to identify modifiers of β-glucocerebrosidase (GCase) activity and expression in Parkinson’s disease (PD) relevant cell models. We secondly aim to ascertain…
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