Mosaicism for somatic SNCA copy number variants in multiple system atrophy is related to pathological subtype and presence of α-synuclein inclusions
Objective: To investigate the correlation of somatic copy number variants (CNVs) of the alpha-synuclein gene (SNCA) in multiple system atrophy (MSA) with disease subtype, and…Assessment of non-motor symptoms of Parkinson’s disease in the long-term follow-up after the cell therapy
Objective: To evaluate the results of the introduction of MSCs on the non-motor symptoms in patients with PD within 12 months after the cell therapy.…A qualitative study exploring the treatment burden and capacity of people with Parkinson’s and their caregivers
Objective: To explore experiences of treatment burden and capacity in Parkinson’s and identify potentially modifiable factors that can improve this Background: Treatment burden, the workload…Volumetric analysis of the Corpus Callosum in Hereditary Cerebellar Ataxia
Objective: To analyze corpus callosum (CC) volumes on MRI in patients under follow-up for confirmed or suspected hereditary cerebellar ataxia Background: It is recognized that…Subclinical cognitive patterns of caudate-anchored connectivity in early Parkinson’s disease
Objective: This study is aimed at elucidating the changes of cognitive connectivity according to orthostatic stress in early Parkinson’s disease (PD). Background: 18F-Florbetaben tracer can…Inflammatory biomarkers in newly diagnosed patients with Parkinson’s disease
Objective: To identify a panel of cerebrospinal fluid (CSF) inflammatory biomarkers for Parkinson’s disease (PD) and to compare levels of inflammatory proteins in control subjects…Understanding patient perceptions of the key components of Medication Adherence in PD: a multicenter, international study
Objective: To understand how patients with Parkinson's disease (PD) and their care partners describe medication adherence. Background: Medication adherence in is a complex construct, associated…Data-driven identification of distinct fronto-subcortical and cortical-posterior subtypes of cognitive decline in Parkinson’s disease
Objective: To use a novel data-driven approach, Subtype and Stage inference (SuStain)[1], for identifying distinct subtypes of domain-specific cognitive decline in Parkinson’s disease (PD), and…Speech disorders and axial motor impairment in advanced Parkinson’s Disease: two sides of the same coin?
Objective: To examine possible correlations between axial motor features, disease severity and speech parameters in advanced Parkinson’s Disease (PD) patients and to evaluate chronic dopaminergic…Feasibility of using mobile technology for aerobic exercise management in people with Parkinson’s disease
Objective: To examine the usability of a smartwatch heart rate monitor for monitoring aerobic exercise compliance during a 6-month brisk walking program, and to evaluate…
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