Feasibility of using wearable sensors to monitor activity and sleep patterns in inpatients with delirium and Parkinson’s disease
Objective: To assess the feasibility of using wearable sensors in Parkinson's disease (PD) inpatients with/without delirium and to quantify clinically relevant digital outcomes to facilitate…Monitoring disease course by sensor-based gait analysis: gait symmetry and motor impairment progression in Parkinson’s disease.
Objective: Evaluate gait symmetry index as progression marker for motor impairment in patients with Parkinson’s disease (PD). Background: PD is a neurodegenerative disease characterized by…Conservative iron chelation for Neuroferritinopathy
Objective: Evaluate the safety and efficacy of a conservative mode of iron chelation with deferiprone 30 mg/kg/day in neuroferritinopathy to limit iron-related neurodegeneration and associated…Repetitive Transcranial Magnetic Stimulation to the Inferior Parietal Lobule in Task-Specific Focal Hand Dystonia: A Randomized Crossover Blinded Outcome Assessment Study
Objective: We used repetitive transcranial magnetic stimulation to test the hypothesis that an inhibitory protocol to the left inferior parietal lobule in right-handed patients with…Is there a role for safinamide in atypical parkinsonian syndromes?
Objective: To search for possible benefits of safinamide in atypical parkinsonism. Background: Safinamide is a selective reversible monoamine oxidase-B inhibitor with both dopaminergic and glutamatergic…Expanding the services of Neurogenetic Clinic – Lessons learnt from Cerebellar Ataxia cohort
Objective: We present an overview of patients seen by our Neurogenetic Clinic since 2019, focusing on the cerebellar ataxia (CA) cohort. Background: Diagnostic yield of…mGlu3 receptors in Parkinson’s disease as a candidate target for neuroprotective therapy: evidence from preclinical studies to human genetic.
Objective: In a toxicological model of mouse parkinsonism through chronic injection of MPTP, we examined whether the presence or absence of mGlu3 receptors affected neurodegeneration…Spinal cord stimulation for gait problems in Parkinson´s disease: Long term report and placebo viability
Objective: In the present study we set out to report a very long-term follow-up period of spinal cord stimulation (SCS) for Parkinson's Disease (PD) patients…Assessment of the long-term effects of STN-DBS on axial symptoms in PD patients through a standardized clinical-instrumental approach
Objective: To evaluate the long-term effects of bilateral STN-DBS and levodopa on axial symptoms in PD patients and the possible correlations between speech and gait…Dopamine neuron platform for screening molecular mechanisms and inhibitory drugs against alpha-synuclein aggregation
Objective: Optimization of a dopamine neuron based,in vitro platform is beneficial for studying molecular mechanisms of alpha-synuclein aggregation,and screening of inhibitory drugs and deducing their…
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