Relations between subthalamic alpha oscillations and motor control impairment in Parkinson’s Disease patients
Objective: Our goal was to investigate subthalamic movement-related oscillatory dynamics in PD patients with different symptom severity. Background: Stable oscillations at frequencies 8-30 Hz in…Gait ataxia and Autonomic dysfunction as early signs of Creutzfeldt-Jakob Disease: A Case Report
Objective: To highlight unusual early presenting symptoms of Sporadic Creutzfeldt-Jakob Disease (sCJD). Background: Prion diseases, a group of rare and fatal diseases caused by an…HAB-C murine model present reactive adult neurogenesis and astrogliosis in adult brain
Objective: To analyze the adult neurogenic response to a neurodegenerative process due to H-ABC tubulinopathy. Background: H-ABC is a neurodegenerative disease caused by mutations in…4 YEARLONG POST PARTUM AUTOIMMUNE CHOREA AS INITIAL PRESENTATION OF INCOMPLETE SLE/APS
Objective: The aim is to report a case of a 4 yearlong postpartum autoimmune chorea secondary to incomplete SLE/APS. Background: Chorea is a movement disorder…Mutational effects of LRRK2 I1371V in astrocytes derived from patient specific iPSCs
Objective: To identify the LRRK2 I1371V mutational effects on astroglial biology involving glutamate metabolism and glutathione machinery. Background: The underlying cause of most of the familial…Hemichorea-hemiballismus syndrome without damage to the subthalamic nucleus?
Objective: Discuss a case of Non-ketotic hyperglycemia hemiballismus hemichorea that preserves the subthalamic nucleus (STN). Background: Non-ketotic hyperglycemia hemiballismus hemichorea is a pathology characterized by…Successful treatment of Stiff Person Syndrome with botulinum toxin
Objective: Describe a case of Stiff Person Syndrome (SPS) treated with botulinum toxin injection and alert to the utility of botulinum toxin in this disorder.…Effect of KW-6356, a novel adenosine A2A receptor antagonist/inverse agonist, on motor and non-motor symptoms in Parkinson’s disease patients as an adjunct to levodopa therapy: Results of Phase 2b study
Objective: To evaluate the efficacy and safety of KW-6356 in Parkinson’s disease (PD) patients with levodopa therapy, irrespective of the presence of wearing-off (WO). Background:…Use of apomorphine infusion pump in the elderly population : a 5 years follw up study on efficacy, safety and tolerability in a cohort bases study
Objective: Evaluate the efficacy, tolerability and safety of subcutaneous apomorphine infusion in elderly patients with advanced Parkinson's disease in a five years follow up cohort. Background: Continuous infusion by subcutaneous apomorphine pump has…Testamentary Capacity Assessment Tool (TCAT): An update report
Objective: The present study reviews all studies about TCAT and its use in clinical settings, as well as its validation in different cultures. Background: TCAT…
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