Comparing duodenal levodopa infusion based on length of treatment in advanced Parkinson’s.
Objective: In this study we seek to compare characteristics and complications of patients suffering from advanced Parkinson's treated with duodenal levodopa infusion. Background: Motor fluctuations…Pilot study of narrative medicine (NM) interventions in facilitating advance care planning (ACP) in Parkinson’s disease (PD): a feasibility study
Objective: To demonstrate the feasibility of conducting NM interventions in PD and to describe NM’s potential impact upon ACP. Background: ACP is associated with increased…The development of a screening tool to identify movement disorders in patients with inborn errors of metabolism
Objective: To develop a user-friendly rapid screening tool for non-movement disorder specialists to detect movement disorders in patients with inborn errors of metabolism. Background: Movement…Alterations of the gustatory circuit underly taste disturbances after lesional tremor therapy with MRgFUS
Objective: Identification of structural brain alterations in patients with essential tremor (ET) reporting taste disturbances after magnetic resonance-guided focused ultrasound (MRgFUS) treatment. Background: Paraesthesias and…Temporal dynamics and longitudinal predictors of apathy in Parkinson’s disease
Objective: To determine how apathy varies across different disease stages of Parkinson’s disease (PD) and the longitudinal predictors of its development, using a large PD…Phase-amplitude coupling between beta power and high frequency oscillations as a sensitive marker of parkinsonian state.
Objective: The aim of this work was to study the potential clinical usefulness of the phase-amplitude coupling (PAC) between beta power and high frequency oscillations (HFO´s).…Ballet for Parkinson’s disease, a new concept: Remote delivery via the English National Ballet’s Dance for Parkinson’s programme
Objective: To explore the characteristics and subjective outcomes for People with Parkinson’s (PwP) attending online Dance for Parkinson’s sessions professionally delivered by the English National…Safety and tolerability of Nilotinib in patients with Huntington’s disease
Objective: To investigate the safety and tolerability of nilotinib, an FDA-approved drug for leukemia, in individuals with Huntington’s disease (HD). Background: Previous clinical studies in…Comorbid neuropathological features in multiple system atrophy
Objective: To elucidate the distribution of comorbid neuropathology in multiple system atrophy (MSA) and its clinical correlation. Background: Multiple protein accumulations are often present in…Administration of the mGlu2 positive allosteric modulator BINA as monotherapy improves parkinsonism in the MPTP-lesioned marmoset
Objective: To assess the effect of selective metabotropic glutamate type 2 (mGlu2) receptor activation on parkinsonism as monotherapy in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned marmoset compared to…
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