Machine learning-based classification of SCA1, SCA2, and Healthy controls using graph features
Objective: To differentiate genetic variants of spinocerebellar ataxia (SCA1 and SCA2) and healthy controls using machine learning on resting-state functional Magnetic Resonance Imaging graph features.…Plasma p-Tau181 and p-Tau231 in Parkinson’s Disease
Objective: To explore whether plasma phosphorylated tau (p-Tau) 181 and p-Tau231 levels are associated with cognition in a Parkinson’s Disease (PD) cohort. Background: We recently…Second Project: The feasibility and efficacy of virtual visits compared to in-person visits for management of Parkinson’s disease. A pilot, international, longitudinal, multicenter trial (NCT04695353).
Objective: To investigate the feasibility and efficacy of virtual visits for Parkinson's Disease (PD) compared to in-person visits. Background: Considering the limited access to specialists…Type 2 diabetes-associated transcriptomic changes in Parkinson’s disease and non-neurodegenerative control brains.
Objective: To evaluate the effect of type 2 diabetes (T2D) on gene transcription in Parkinson’s disease (PD) and non-neurodegenerative control brains. Background: People with T2D…Dynamical modulations of low frequency deep brain stimulation on axial symptoms in Parkinson’s disease
Objective: First, we aimed to evaluate the optimal contact to address axial symptoms with low frequency deep brain stimulation (LFS). Second, we aimed to evaluate…A systematic review to compare the effect of bilateral deep brain stimulation (STN versus GPI) on gait and balance in Parkinson’s disease
Objective: To compare the effect of bilateral sub-thalamic nucleus (STN) deep brain stimulation (DBS) and Globus pallidus interna (GPI) DBS on gait and postural stability in Parkinson’s…LRRK2 and GBA major variants in the New York Mount Sinai BioMe Biobank
Objective: To characterize the frequency of major LRRK2 and GBA variants in a multi-ethnic New York cohort with and without Parkinson disease (PD). Background: There…Influence of alcohol consumption on cognitive decline in Parkinson disease.
Objective: To assess whether alcohol consumption (AC) is independently associated with cognitive decline (CD) in PD. Background: AC is linked to dementia and neurological damage…Dynamic functional connectivity changes and striatal dopamine deficiency in Parkinson’s disease
Objective: Using a multimodal neuroimaging approach, we assessed whether striatal dopamine synthesis capacity modulates the temporal dynamics of FC in PD. Background: The novel approach…Embodied language in Parkinson disease: the case of demonstrative
Objective: Action language is recognized as impaired in Parkinson's disease (PD), proposing a functional role for the motor system in understanding action words [1]. This…
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