Theoretical Definition of DBS Electrode Misplacement
Objective: To propose a definition of Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) electrode misplacement (MP) based on ideal brain connectivity strength. Background: MP is defined…Isolated ZIC-4 antibody associated cerebellar dysfunction triggered by Tuberculosis
Objective: We report a very rare case of isolated ZIC4 associated rapidly progressive cerebellar syndrome occurring in the background of bone marrow tuberculosis. Background: Rapidly…LRRK2 G2019S promotes astrocytic inflammatory response induced by oligomeric α-synuclein through NF-κB pathway
Objective: Analyzing the mechanism of inflammatory response induced by oligomeric α-synuclein (O-αS) in LRRK2 G2019S mutation astrocytes to provide new targets and ideas for the…The impact of anxiety symptoms and treatment on Parkinson’s disease-related disability: findings from the Parkinson’s Progression Markers Initiative
Objective: To determine the functional consequences of baseline anxiety symptoms and the longer-term impact of initiation of anxiety treatment in Parkinson’s disease (PD). Background: While…Hemifacial Spasm: Recent experience in a movement disorders reference center in Chile
Objective: To analyze the demographic characteristics of patients with HFS and their response to different BoNT at the center for movement disorders CETRAM in Santiago,…Safinamide in Parkinson´s Disease. A retrospective study
Objective: To evaluate the safety of safinamide in Parkinson´s Disease (PD) and determine consequences of direct switch from rasagiline. Background: A wash-out period is recommended…Deep Brain Stimulation for Orthostatic Tremor: An observational study’
Objective: To evaluate the efficacy of stimulation near the DRT on OT, based on standing time and QoL, and relate the proximity of stimulation to…A Phase 2, Double-blinded, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of ABP-450 (PrabotulinumtoxinA) in Adults with Isolated Cervical Dystonia
Objective: To evaluate the safety and the efficacy of ABP-450 (prabotulinumtoxinA) in patients with cervical dystonia (CD). Background: ABP-450 (prabotulinumtoxinA) is a new 900kDA botulinumtoxinA.…Pilot study incorporating outcome measures after paediatric deep brain stimulation with patient and carer expectations and satisfaction
Objective: To pilot a multi-faceted evaluation framework for paediatric patients undergoing deep brain stimulation (DBS) in a single centre. Background: DBS can be useful for…Sleep disorders in Parkinson’s disease patients. A case-control study.
Objective: To determine the quality of sleep, the type of sleep disorders and their correlations with motor impairment in Parkinson's disease (PD) patients. Background: Sleep…
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