Design of a Phase 2 Study of Suvecaltamide in Moderate to Severe Parkinson’s Disease Tremor
Objective: Describe the design of a phase 2 study (NCT05642442) of a once-daily, extended-release formulation of suvecaltamide to treat moderate to severe Parkinson’s disease tremor…Publication rates and characteristics of clinical trials in deep brain and responsive neurostimulation
Objective: We examine DBS and RNS trials from 1997-2022, chart their characteristics, and examine rates and predictors of results reporting. Background: Prompt dissemination of clinical…Harmonizing genetic testing for early-onset Parkinson’s disease: results of the PARKNET multicentric study
Objective: To harmonize the interpretation of genetic testing in Parkinson's disease (PD) across the PARKNET network, as well as to provide a comprehensive assessment of…Open-label Extension Study of Long-term Safety and Tolerability of Foslevodopa/Foscarbidopa for Treatment of Advanced Parkinson’s Disease
Objective: To evaluate long-term safety/tolerability of foslevodopa/foscarbidopa (LDP/CDP) in patients with advanced Parkinson’s disease (aPD) in a phase 3 open-label extension (OLE) study. Background: LDP/CDP…Understanding neuropsychological features of dopa responsive dystonia in children
Objective: To describe the neuropsychological features in five siblings with dopa responsive dystonia (DRD) due to autosomal dominant GCH1 related disease (AD GCH1). Background: Although…Spontaneous intracranial hypotension presenting with progressive cerebellar ataxia and myelopathy
Objective: To highlight an infrequent, treatable cause of ataxia and myelopathy. Background: Spontaneous intracranial hypotension (SIH) typically presents with postural headache. Occasionally, MRI may show some…Risk factors of sleep disordered breathing in Veterans with Parkinson’s disease.
Objective: To investigate factors associated with the risk of sleep disordered breathing (SDB) in Veterans with Parkinson's disease (PD). Background: Sleep disordered breathing is common…Neural activity in pedunculopontine nucleus during sleep
Objective: Assess neural activity in various brain areas in sleep versus wakefulness in pediatric patients with movement disorders Background: Pedunculopontine nucleus (PPN) is believed to…Parkinson’s Team Training is beneficial for new and established PD Centers
Objective: To determine if the Parkinson’s Foundation (PF) Parkinson’s disease (PD) Team Training (TT) empowers Parkinson’s interprofessional healthcare teams to make changes in their care…Genetic diagnosis of parkinsonian phenotype of Machado Joseph Diseasep (SCA-3) presenting with dopa induced dyskinesia
Objective: We report a rare type IV parkinsonian phenotype of MJD having a rare genetic mutation. SCA type 3 (SCA3), also known as Machado-Joseph disease…
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