Identification of atlastin genetic modifiers in a Hereditary Spastic Paraplegia model in Drosophila
Objective: To identify genetic modifiers of decreased locomotion and neuromuscular junction defects associated with atlastin knockdown in motor neurons. Background: Hereditary spastic paraplegias (HSPs) are…Are GDNF receptors the gatekeepers of GDNF efficacy during progressive nigrostriatal neuron loss?
Objective: To determine if GDNF receptor expression levels in the striatum or substantia nigra (SN) change in relation to differences in tyrosine hydroxylase (TH) and…Corticobasal Syndrome (CBS), Corticobasal Degeneration (CBD) and Progressive Supranuclear Palsy (PSP) Cohort in Central New York
Objective: Aims: The goal of this retrospective study was to characterize a CBS, CBD and PSP cohort and demonstrate that the Electronic Medical Record (EMR)…Transition among HD-ISS stages as an endpoint in clinical trials for HD
Objective: Investigate the time to the event of HD-ISS Stage 3 transition (functional change) as an endpoint for clinical trials in Huntington’s disease (HD) and…Diffusion Tensor Imaging of Spinocerebellar ataxia type 12 patients in comparison of Healthy control
Objective: To assess changes in brain tissue microstructures using diffusion tensor imaging parameters, fractional anisotropy (FA), increased radial (RD) and axial diffusivities (AD) in SCA…Characteristics of cases in which stimulation was programmed for multiple targets in deep brain stimulation therapy for Parkinson’s disease.
Objective: To clarify the the clinical background of Parkinson's disease patients with DBS who received multiple stimulus targets. Background: Deep brain stimulation (DBS) is an…Association between Stress and Bruxism in Egyptian University Female Students Throughout Their Final Exam Period
Objective: The Current study highlights the correlation between bruxism and stress in a group of Egyptian university students. Background: Bruxism is an involuntary contraction of…The effect of APOE ε4 on striatal vesicular monoamine transporter-2 density in Parkinson’s disease
Objective: To evaluate the effect of apolipoprotein E 4 (APOE 4) on striatal vesicular monoamine transporter-2 (VMAT2) density in Parkinson’s disease (PD).To evaluate the effect…Effect of ADX-88178, a highly-selective mGlu4 PAM, on parkinsonism, dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset
Objective: To investigate the effect of the metabotropic glutamate 4 (mGlu4) positive allosteric modulator (PAM) ADX-88178 on parkinsonism, dyskinesia and psychosis-like behaviours (PLBs) in the…Metoclopramide-induced acute dystonic reaction caused by CYP2D6 *4/*4 and CYP2D6 *10/*10 genotypes
Objective: Objective is to demonstrated the role of CYP P450 2D6 polymorphisms in metoclopramide-induced acute dystonic reactions. Background: Metoclopramide can induce acute extrapyramidal reactions by…
- « Previous Page
- 1
- …
- 10
- 11
- 12
- 13
- 14
- …
- 186
- Next Page »