Genetics of Parkinson’s Disease in Polish patients with positive family history-preeliminary study.
Objective: The aim of our study was to find genetic variants associated with the familial forms of Parkinson’s disease (PD) in Polish population. Background: PD…Genetic polymorphisms associated with nigrostriatal dopaminergic depletion as measured with [I123]-FP-CIT SPECT in Parkinson’s disease
Objective: To conduct a genome-wide association study (GWAS) of striatal [I123]-FP-CIT SPECT signal as endophenotype to explore possible associations between genetic background and nigrostriatal dopaminergic…Anti-tremor efficacy of Nabiximols (JZP378) in a rat Model of essential tremor
Objective: To assess the effect of acute and subchronic oral administration of nabiximols (JZP378), a complex botanical cannabinoid drug mixture with Δ9-tetrahydrocannabinol (THC) and cannabidiol…Short-term effect of continuous positive airway pressure in MSA patients with sleep disordered breathing
Objective: SBD are frequent in MSA, mainly represented by inspiratory stridor, obstructive and central sleep apnea/hypopnea syndrome (SAS), or hypopneaimpacting the quality of sleep. A…Cerebellar volumetry in SCA1, SCA3, SCA6, MSA-C, and SAOA
Objective: We aim to identify volume differences in the cerebellum between spinocerebellar ataxia type 1 (SCA1), SCA3, SCA6, multiple-system atrophy, cerebellar type (MSA-C), and sporadic…Machine learning classifies Parkinson’s Disease and Progressive Supranuclear Palsy on saccade, pupil, and blink measures during a naturalistic free-viewing task
Objective: Eye tracking has been suggested as a source of prospective biomarkers in Parkinson’s Disease (PD), and recent work has demonstrated the use of machine…Continuous subcutaneous levodopa/carbidopa infusion with ND0612 for Parkinson’s disease: Three-year data from the open-label BeyoND study
Objective: To evaluate three-year outcomes from the ND0612 BeyoND study. Background: Investigational ND0612 is in development as a 24-hour continuous, subcutaneous infusion of liquid levodopa/carbidopa…Motor complications in Parkinson’s disease
Objective: To determine the presence, severity, functional impact and predisposing factors of motor complications. Background: Motor complications are well recognized in Parkinson’s disease (PD), but…Timed-up-and-go tests under dual-task conditions: Influence of different tasks on gait parameters in Parkinsonian patients
Objective: To analyse the effect of dual tasking on the Parkinson gait. Background: Parkinson's disease has a strong impact on gait and posture, leading to…Clinical analysis of Levodopa/carbidopa intestinal gel infusion in advanced Parkinson’s disease. A single-center retrospective cohort study.
Objective: To evaluate clinical impact of treatment (LCIG) infusion in patients with advanced PD. Background: Levodopa/carbidopa intestinal gel (LCIG) infusion has demonstrated more stable plasma…
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