Psilocybin therapy for depression and anxiety associated with Parkinson’s disease: a pilot study (NCT04932434)
Objective: To investigate the safety, tolerability, feasibility, and preliminary efficacy of moderate and high dose psilocybin treatment with psychotherapeutic support for comorbid Parkinson's disease (PD)…Effects of physical exercise interventions on cognitive function in Parkinson’s disease: an updated systematic review and meta-analysis of randomized controlled trials
Objective: To determine whether physical exercise interventions can improve cognitive function, including overall performance and specific domains, in patients with Parkinson’s disease (PD) and to…The natural history of Parkinson’s disease in LRRK2 G2019S carriers
Objective: To document differences between the evolution of self-reported symptoms and prodromal markers in LRRK2 G2019S carriers and non-carriers with and without Parkinson’s Disease (PD).…Can very early levodopa prevent self-injury in Lesch-Nyhan Disease?
Objective: To determine whether levodopa treatment starting at a very young age can prevent the development of the full clinical phenotype in Lesch-Nyhan disease. Background:…Severe tacrolimus-induced parkinsonism after kidney transplantation
Objective: To describe a kidney transplant recipient with severe tacrolimus-induced parkinsonism. Background: Kidney transplant recipients have to adhere to strict immunosuppressive regimens, which generally include…Longitudinal free-water changes in dementia with Lewy bodies
Objective: To characterize longitudinal diffusion microstructural changes in individuals with dementia with Lewy bodies (DLB). Background: Diffusion-weighted MRI (dMRI) examines tissue microstructure integrity in vivo.…Drivers of longitudinal healthcare cost in Parkinson Disease
Objective: To identify associations between baseline patient and disease characteristics, and longitudinal healthcare costs in Parkinson disease (PD). Background: Disease prevalence, disability-adjusted life-years, and PD…Neurological symptom severity in Wilson disease is associated with increased white matter mean diffusivity
Objective: To evaluate the relationship between white matter (WM) changes and neurological impairment in Wilson disease (WD). Background: Neuroimaging biomarkers derived from diffusion tensor imaging…Touchscreen nQ application as a remote digital biomarker in Parkinson disease
Objective: To characterize the viability of nQ machine learning platform via touchscreen keyboard as a digital biomarker for Parkinson disease Background: To date, a reliable…Intrarater and interrater reliability of the 3 meter backward walk test in individuals with Parkinson disease.
Objective: Determine the intrarater and interrater reliability of the three meter backward walk (3 MBW) test for individuals diagnosed with Parkinson Disease. Background: Background- Parkinson…
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