Preoperative motor deficits and depressive symptoms predict quality of life in patients with Parkinson’s disease at different time points after surgery for subthalamic stimulation.
Objective: This retrospective study explored whether preoperative motor, cognitive, and affective parameters predict QoL and QoL components at 6 and 12 months after STN-DBS surgery.…Brain MRI volumetry analysis for patients with Parkinson’s disease suffering from REM sleep behavior disorder: a pilot study
Objective: To detect patients with Parkinson's disease that have REM sleep behavior disorder (RBD) and perform brain MRI volumetry analysis. Background: Parkinson’s disease is classically…The Link between Handedness and Prevalence of Writer’s Cramp – A Systematic Literature Review
Objective: The link between handedness and the prevalence of writer’s cramp has not been investigated yet. In this systematic review, the distribution of handedness was…Neurofilament light chain in Huntington’s Disease Like 2: a cross-sectional comparison with Huntington’s Disease.
Objective: The objective of this study was to assess the levels of Neurofilament light chain (NfL) in the blood plasma of patients diagnosed with HDL2…Examining the Correlation Between Multi-Spectral Diffusion Weighted Imaging Quantitative Maps and Unified Parkinson’s Disease Rating Scale Scores
Objective: We aimed to correlate Unified Parkinson’s Disease Rating Scale (UPDRS) scores with quantitative maps to determine the ability to generate non-invasive biomarkers for Parkinson’s…Olfactory dysfunction as a predictor of the future development of parkinsonism in COVID patients
Objective: Olfactory dysfunction due to SARS-CoV-2 infection as a prodromal stage of PD. Background: Olfactory dysfunction due to SARS-CoV-2 disease can depend on the neuroinvasive properties…Effect of deep brain stimulation on dysphagia in Parkinson’s disease: A Systematic Review
Objective: To evaluate the effects of deep brain stimulation (DBS) on dysphagia in Parkinson's disease (PD) patients. Background: Although DBS in the subthalamic nucleus (STN)…Was the deep brain stimulation surgery successful? Is it the same for the physician and the patient ?
Objective: To compare the physician`s assessment and the patient perception of the definition of successful therapy in STN DBS. Background: Although the treatment of Parkinson's…LRRK2 Inhibition by BIIB122/DNL151 Demonstrates Robust Target and Lysosomal Engagement: Pharmacokinetics, Pharmacodynamics and Safety in Phase 1 and Phase 1b Studies in Healthy and Parkinson’s Participants
Objective: To characterize the pharmacokinetics (PK), pharmacodynamics, safety, and exposure-response (E-R) relationships of BIIB122/DNL151 to inform on clinical dose selection. Background: Increased LRRK2 kinase activity…Nucleus basalis of Meynert and total gray matter atrophy are related to cognitive and gait decline in Parkinson’s disease
Objective: To assess the associations between the nucleus basalis of Meynert (NBM) and total grey matter atrophy with cognitive phenotype and gait measures in a…
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