Relationship between balance performance and corticomotor Inhibition in individuals with Parkinson’s disease
Objective: To explore the possible relationship between corticomotor inhibition assessed by transcranial magnetic stimulation (TMS) and balance performance in individuals with Parkinson’s disease (PD). Also,…Image-guided programing in useful in DBS for Parkinson’s disease
Objective: To evaluate the utility of image-guided DBS programming; to determine the correlation between optimal DBS electrode placement predicted by imaging-guided software and monopolar review…Tramadol Induces Neuroinflammation, Mitochondrial Oxidative Stress, Neurotransmitters Dysbalanced and Produced Parkinson’s Disease Like Symptoms in Experimental Wistar Rats
Objective: The current study is designed to evaluate the possible neurotoxic effects of tramadol in Wistar rats. Background: Parkinson’s disease (PD) is a chronic neurodegenerative…A staged screening paradigm to identify people at risk of Parkinson’s disease in the Parkinson’s Progression Markers Initiative
Objective: To identify people at risk of Parkinson’s disease (PD) using a staged-screening paradigm. Background: Early recognition of people with PD may be essential to…A white matter disease with blooming grey matter
Objective: To describe a case of LMNB1-related autosomal dominant leukodystrophy with unique radiological features. Background: Autosomal dominant leukodystrophy (ADLD), caused by the duplication of the…Ramelteon ameliorates abnormal sleep-wake behavior in a zebrafish model of Parkinson’s disease by facilitating abnormal lipid metabolism
Objective: The study aims to explore the role of melatonin receptor 1 (MT1) in the regulation of sleep-wake behavior in rotenone-induced Parkinson's disease (PD) model…Long-term outcomes after subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson’s Disease (PD) in Singapore
Objective: To evaluate the long-term outcomes of subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson’s Disease (PD) up to 10 years after surgery.…Neurogenic orthostatic hypotension is not associated with generalized dysautonomia in early motor PD
Objective: We aim to assess the relationship between neurogenic Orthostatic Hypotension (nOH) and general dysautonomia in an early motor PD cohort. Background: Dysautonomia is a…Impaired CaMKII/ERK activation in mouse mutant LRRK2 R1441G fibroblasts was associated with reduced mitochondrial calcium store and efflux in response to depolarization stress
Objective: To determine the molecular link of LRRK2R1441G mutation to impaired CaMKII/ERK signaling under mitochondrial depolarization stress using mutant mouse embryonic fibroblast (MEF) model of…Epidemiological, clinical and paraclinical characteristics of paroxysmal dystonia in multiple sclerosis : A study of Tunisian cohort
Objective: To describe the specificities of paroxysmal dystonia (PD) in a cohort of Tunisian Multiple Sclerosis (MS). Background: Movements disorders are uncommon in multiple sclerosis.…
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