The Critical Path for Parkinson’s Consortium approach to developing consensus recommendations for neuroimaging biomarkers appropriate for use in Parkinson’s disease drug development
Objective: To develop consensus recommendations for neuroimaging biomarkers suitable for use in Parkinson’s disease (PD) drug development. Background: Given the anticipated rise in PD prevalence…Dopamine Receptor Gene Polymorphism in L-Dopa Induced Dyskinesia- A Study from Eastern India
Objective: We intended to find the frequency of Single Nucleotide Polymorphism (SNP) rs6280 in DRD3 gene in PD patients with and without Levodopa Induced Dyskinesia…Apparition of a thalamic hand after focused ultrasound thalamotomy
Objective: To report the occurrence of a thalamic hand as a rare side effect of MR-guided focused ultrasound (MRgFUS) thalamotomy of the right ventral intermediate…A novel model of care for an integrated movement assessment program (I-MAP) targeted for patients with movement disorders
Objective: To provide an integrated hub where assessment and recommendations on medical, physical, functional, psychosocial needs are made efficiently, and care co-ordination and support services…A 78-year-old man with progressive ataxia, palatal tremor, parkinsonism and motor neuron disease.
Objective: To report a unique case of palatal tremor associated with parkinsonism, ataxia and motor neuron disease. Background: Progressive ataxia with palatal tremor (PAPT) is…6-[18F]fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET striatal binding patterns in patients with Parkinson’s Disease and Parkinson Plus Syndromes.
Objective: In this study we investigate striatal binding patterns in patients with Idiopathic Parkinson’s disease (IPD), compared to those with Parkinson Plus syndromes (PPS) versus…Olfactory dysfunction and neuropsychiatric manifestations in early drug-naïve Parkinson’s disease
Objective: To determine the severity of various neuropsychiatric disturbances in drug-naïve Parkinson’s disease (PD) patients with (PD-OD) and without olfactory dysfunction (PD-NOD) compared to healthy…Transferrin as a possible CSF biomarker in neurodegenerative proteinopathies
Objective: The aim of this study was to determine whether cerebrospinal fluid (CSF) levels of transferrin differ between patients with Parkinson´s disease (PD), multiple system…Patterns of Parkinson disease mitochondrial brain function indexed by 31P magnetic resonance spectroscopy
Objective: To examine whether individuals with PD show greater temporal than frontal high energy phosphate metabolism (31P MRS ATP) that is similar or different from…Distinct temporal and spatial alteration of immunoproteasome in Parkinson’s Disease pathogenesis
Objective: We aimed to investigate the temporal and spatial evolution of immunoproteasome in the central nervous system (CNS) during PD pathogenesis using mouse model. Background:…
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