Chinese herbal medicine treatment based on subgroup differentiation as adjunct therapy for Parkinson’s disease: interim analysis of a pilot add-on, randomized, controlled, pragmatic clinical trial
Objective: This interim data analysis preliminarily evaluated the feasibility and effectiveness of protocolized CHM on motor-related daily living of PD patients. Background: A Chinese national…KINETIC 2: An ongoing phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor
Objective: KINETIC 2 (NCT05173012) is an ongoing, phase 2b, randomized, double-blind, placebo-controlled, dose-response study that aims to evaluate the efficacy, safety, and tolerability of SAGE-324/BIIB124…Foslevodopa/foscarbidopa subcutaneous infusion shows similar infusion site reaction severity score across range of infusion rates in patients with Parkinson’s disease
Objective: Characterize the relationship between foslevodopa/foscarbidopa infusion rate and infusion site reaction (ISR) score in patients with Parkinson’s disease (PD) Background: As PD progresses, motor…Feasibility and efficacy of a multidisciplinary telemedicine intervention program to reduce falls and gait impairment in Parkinson’s disease (NCT04694443).
Objective: To evaluate the feasibility and effectiveness of a multidisciplinary telemedicine intervention program to reduce falls and to improve quality of life (QoL) in patients…Use of levodopa-carbidopa intestinal gel to treat a patient with multiple system atrophy (MSA)
Objective: To describe a case report on the use of Levodopa-carbidopa intestinal gel (LCIG) to treat non-motor symptoms in a patient with multiple system atrophy (MSA) Background: There is no…The crucial role of the visual system on the PISA syndrome in Parkinson’s disease
Objective: Patients with Parkinson's disease (PD) are significantly disturbed in their daily life when accompanied by the PISA syndrome (PS) of lateral bending. Background: We…Angiotensin II Type 1 (AT1) receptor antagonists as potential candidates for anxiety treatment in Parkinson’s Disease
Objective: The aim of this study was to explore the effects of Angiotensin II Type 1 receptor blockers (ARBs) and angiotensin-converting enzyme inhibitors (ACEIs) on…Orthostatic vital sign changes do not influence 5-year motor outcomes in PD
Objective: We assessed whether orthostatic blood pressure (BP) and heart rate (HR) changes in an early motor PD cohort influence motor, and postural instability and…Effects of Motor Subtype Stability on Non-Motor Symptoms in Early Parkinson’s Disease
Objective: To determine the effects of motor subtypes’ stability on non-motor symptoms (NMS) over three years in early Parkinson’s disease (PD). Background: Research have found…Severe movement disorder initially suspected of being conversion – key insights from the psychiatrist
Objective: The review of a case diagnosed as Conversion Disorder (CD) in a University Movement Disorders clinic is presented here. As this patient eventually recovered…
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