Are GBA–Parkinson Disease patients’ good candidates for Deep Brain Stimulation? A Longitudinal Multicentric study on a Large Italian Cohort
Objective: To investigate the impact of GBA variants on the long-term outcome of deep brain stimulation (DBS) in a large cohort of Italian PD subjects…A single centre retrospective study of dual target deep brain stimulation for clinically complex essential and dystonic tremor – a 5-year follow up
Objective: Measure efficacy of dual target deep brain stimulation in pharmaco-refractory tremors. Background: Tremor is characterised by involuntary rhythmic movement present in one or more…Pharmacokinetics, Safety and Tolerability of Foslevodopa/Foscarbidopa Following Continuous Subcutaneous Infusion to Arm, Thigh and Flank compared to Abdomen in Parkinson’s Disease Patients
Objective: To characterize safety/tolerability and pharmacokinetics (PK) of levodopa (LD) and carbidopa (CD) after delivery of foslevodopa/foscarbidopa in Parkinson’s disease (PD) patients at 4 different…Deep brain stimulation and fusion technologies: a synthesis study
Objective: The major thrust is analyzing the large amounts data computationally generated and synthesizing it into useful systems-wide models of biological processes. Background: It is…Stability and predictability of motor symptom control in patients with advanced Parkinson’s disease (aPD) receiving continuous subcutaneous foslevodopa/foscarbidopa (LDP/CDP)
Objective: To evaluate temporal changes in motor states (OFF and ON without troublesome dyskinesia [TD; good ON]) throughout the waking day in patients with aPD…Whole exome sequencing of 67 Swedish Parkinson patients identifies a family with VPS35 D620N
Objective: To determine the usefulness of WES in the diagnostic evaluation of Parkinson’s disease (PD) patients and to set up computational pathways for the identification…Apomorphine effects on Parkinson’s disease fluctuation related pain: a pilot study
Objective: To evaluate the effect and safety of subcutaneous apomorphine as a treatment for fluctuation-related pain in Parkinson's disease (PD). Background: Pain is one of…The Blood-Brain Barrier Integrity and Prevalence of Intrathecal T Helper 17.1 Cells in Huntington´s Disease
Objective: The aim of the study was to investigate the potential role of cerebrospinal fluid (CSF)/plasma albumin quotient (Q-Alb) as a biomarker for blood-brain barrier…Levodopa-entacapone-carbidopa intestinal gel infusion for Parkinson’s disease: An analysis of data collected from the Swedish national register of Parkinson’s disease.
Objective: To investigate efficacy, tolerability, and safety of levodopa-entacapone-carbidopa intestinal gel (LECIG) in Parkinson’s disease. Background: LECIG was introduced in 2019. The approval was based…Efficacy of subthalamic nucleus deep brain stimulation in Parkinson’s disease: A preliminary Thailand experience
Objective: To evaluate the efficacy and adverse events of subthalamic nucleus deep brain stimulation (STN-DBS) in Thai patients with Parkinson’s disease (PD). Background: Bilateral STN-DBS…
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