Sympathetic tone abnormalities in subjects at risk for Parkinson’s Disease without evidence of nigrostriatal neurodegeneration: a multimodal biomarker study
Objective: To study autonomic dysfunction in subjects with idiopathic REM sleep behavior disorder (iRBD) and at least one pre-motor symptom of Parkinson's disease (PD). Background:…Testing gene-environment interaction in Parkinson’s disease (PD) using whole-genome sequencing of pesticide-exposed cohorts.
Objective: To identify interactions of specific pesticides with genetic loci to find causal variants for PD using gene burden analysis (BA). Background: Pesticide exposure is…Oculomotor parameters measured during free viewing of video differentiate Parkinson’s disease from progressive supranuclear palsy
Objective: Characterize oculomotor phenotypes comprised of saccade, pupil, and blink behaviour for progressive supranuclear palsy (PSP) and Parkinson’s disease (PD) with differing degrees of cognitive…Development and Evaluation of a Digital Resource Library for Arkansans with Parkinson Disease and Their Caregivers
Objective: To develop and evaluate impact of a Digital Resource Library (DRL) to address unmet needs for disease state education of People with PD (PwP)…Novel application of the Timed Up and Go Scale as a reliable tool to measure functional improvement and fall prevention after inpatient Parkinson’s Disease specific rehabilitation for advanced stages of PD
Objective: To determine whether the “Timed Up and Go” (TUG) scale can be effectively utilized in patients with advanced Parkinson’s disease (PD) as an outcome…Correlations between bradykinesia and acoustic speech variables in advanced Parkinson’s Disease
Objective: To find the presence of possible correlations between upper extremity bradykinesia and speech variables in different medication conditions in a cohort of advanced Parkinson’s…A multiple-dose thorough QT study to evaluate the effect of ampreloxetine on cardiac repolarization in healthy subjects
Objective: To characterize the effect of therapeutic and supratherapeutic doses of ampreloxetine on cardiac repolarization in healthy subjects. Background: Ampreloxetine is a potent NE reuptake…Association between supine hypertension and plasma free triiodothyronine in drug-naïve Parkinson’s disease
Objective: We aimed to clarify the association between thyroid hormone levels and supine hypertension (SH) in patients with early Parkinson’s disease (PD). Background: Increasing evidence…Influence of square-stepping exercise on brain activation in older adults with cognitive frailty
Objective: To investigate the brain activity induced by square-stepping exercise (SSE), as well as the relationships between brain activity change and SSE performance in older…The effect of taVNS on gait in advanced Parkinsons disease – a double blind, sham controlled motion sensors study in 30 patients
Objective: In this double blind, sham controlled study on 30 advanced Parkinson’s disease (aPD) patients we used inertial motion sensors (IMS) to characterize the effect…
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