Sleep hygiene practice in patients with Parkinson’s disease
Objective: We examined the prevalence of diverse sleep hygiene behavior and their associations with insomnia severity in PD patients.We examined the prevalence of diverse sleep…Radiological markers of CSF α-synuclein aggregation in Parkinson’s disease patients
Objective: To investigate the association between cerebrospinal (CSF) αS aggregates, MRI, and dopamine transporter spectral tomography (DaTscanTM) imaging metrics. Background: Synuclein amplification assays (SAA) enables…Effect of intensive Game-based neurorehabilitation (GBNR) on gait, balance and quality of life (QOL) in Parkinson’s patients: A prospective randomized control study
Objective: To assess changes in the gait, balance and QOL in PD patients subjected to intensive GBNR in comparison with conventional Neurorehabilitation (NR) therapy using…Concealment of Parkinson’s Disease: Prevalence and Impact on Health and Quality of Life
Objective: (1) To explore the proportion and personal characteristics of patients who do not disclose their diagnosis of Parkinson's disease (PD) to their family, and…Underutilization of Neurology and Rehabilitation Services among People with Parkinson’s Disease
Objective: to map utilization of neurology and rehabilitation services by people with Parkinson’s disease (PD), and to identify associations between utilization and demographics. Background: People…The impact of wearing ‘OFF’ (WO) episodes on non-motor symptoms (NMS) burden and quality of life (QoL) in Parkinson’s disease (PD) patients
Objective: To estimate the frequency and severity of NMS and their impact on QoL among patients with moderate to advanced PD with WO episodes versus…Safety and efficacy of P2B001 (low dose combination of extended-release pramipexole and rasagiline) in patients with early Parkinson’s disease: Subgroup analyses from a randomized, controlled trial
Objective: Evaluate the efficacy and safety of P2B001 for different subgroups of patients with early Parkinson’s disease (PD). Background: P2B001 is an investigational, fixed low-dose,…Controlled-release zolpidem improves freezing of gait and levodopa-induced dyskinesias in a patient with Parkinson’s disease.
Objective: To report a patient with Parkinson’s disease with freezing of gait and levodopa-induced dyskinesias who improved with zolpidem. Background: A 57-year-old man developed Parkinson’s…Relationship between agricultural vulnerability to organic compound fungicides and herbicides and Parkinson’s disease incidence in rural population in northern India
Objective: In the Indian agricultural health study cohort, we evaluated the relationship between prospective exposures to organic fungicides and herbicides and the incidence of Parkinson's…TREM2 maintain microglial proliferation and α-syn accumulation in PD models via the PI3K-Akt pathway
Objective: To investigate the effect and role of TREM2 in microglial proliferation, α-syn-associated pathology and dopaminergic degeneration in Parkinson’s disease (PD). Background: PD is characterised…
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