A staged screening paradigm to identify people at risk of Parkinson’s disease in the Parkinson’s Progression Markers Initiative
Objective: To identify people at risk of Parkinson’s disease (PD) using a staged-screening paradigm. Background: Early recognition of people with PD may be essential to…A white matter disease with blooming grey matter
Objective: To describe a case of LMNB1-related autosomal dominant leukodystrophy with unique radiological features. Background: Autosomal dominant leukodystrophy (ADLD), caused by the duplication of the…Ramelteon ameliorates abnormal sleep-wake behavior in a zebrafish model of Parkinson’s disease by facilitating abnormal lipid metabolism
Objective: The study aims to explore the role of melatonin receptor 1 (MT1) in the regulation of sleep-wake behavior in rotenone-induced Parkinson's disease (PD) model…Long-term outcomes after subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson’s Disease (PD) in Singapore
Objective: To evaluate the long-term outcomes of subthalamic nucleus deep brain stimulation (STN-DBS) in patients with Parkinson’s Disease (PD) up to 10 years after surgery.…Neurogenic orthostatic hypotension is not associated with generalized dysautonomia in early motor PD
Objective: We aim to assess the relationship between neurogenic Orthostatic Hypotension (nOH) and general dysautonomia in an early motor PD cohort. Background: Dysautonomia is a…Impaired CaMKII/ERK activation in mouse mutant LRRK2 R1441G fibroblasts was associated with reduced mitochondrial calcium store and efflux in response to depolarization stress
Objective: To determine the molecular link of LRRK2R1441G mutation to impaired CaMKII/ERK signaling under mitochondrial depolarization stress using mutant mouse embryonic fibroblast (MEF) model of…Epidemiological, clinical and paraclinical characteristics of paroxysmal dystonia in multiple sclerosis : A study of Tunisian cohort
Objective: To describe the specificities of paroxysmal dystonia (PD) in a cohort of Tunisian Multiple Sclerosis (MS). Background: Movements disorders are uncommon in multiple sclerosis.…Health status of Lewy Body Dementia caregivers predicts psychological response to peer mentoring intervention
Objective: To understand how caregiver health status influences response to a peer mentoring intervention in caregivers of individuals with Lewy Body Dementia (LBD). Background: Caregiving…Globus pallidus interna deep brain stimulation for Parkinson’s Disease: Impact on Restless Legs Syndrome
Objective: The goal of this study was to evaluate the impact of deep brain stimulation (DBS) of the globus pallidus interna (GPi) on Restless Legs…Jerky dystonic hand revisited: post-stroke thalamic tremor
Objective: To assess phenomenology and clinical- radiological correlation of post thalamic stroke movement disorders (MDs) Background: Post stroke movement disorders (PSMD) are rare and have…
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