Alterations of gait as an early marker of incipient alpha-synucleinopathy
Objective: To investigate early motor signs of α-synucleinopathies in patients with isolated REM sleep behavior disorder (iRBD) using gait analysis. Background: iRBD is an early…Motor subtype stability and cognitive profiles in early Parkinson’s disease
Objective: To examine the association between motor subtypes’ stability and cognitive assessment scores across three years in early Parkinson’s disease (PD). Background: Past studies have…An in-vivo study of regional synaptic density loss in patients with Multiple System Atrophy using [11C]UCB-J PET molecular imaging.
Objective: We present preliminary, cross-sectional data, on the in-vivo evaluation of pre-synaptic terminal density in the brain of patients with Multiple System Atrophy (MSA) compared…Calcium phenotype in cellular models of VPS13A disease
Objective: Since the Membrane contact sites (MCS) between ER and mitochondria are of particular importance for cellular calcium homeostasis, we hypothesize that MCS dysfunction in…Distinct striatal connectivity patterns in patients with Parkinson’s disease with and without urinary symptoms
Objective: To investigate the potential effect of urinary symptoms on the regional striatal functional connectivity (FC) in a cohort of drug-naïve PD patients applying a…Progressive myoclonus ataxia and resting tremor in hypoceruloplasminemia
Objective: To describe two familiar cases of hypoceruloplasminemia presenting with movement disorders Background: Aceruloplasminemia is a metabolic disorder caused by mutations in the ceruloplasmin (CP)…Patterned alternating-coloured strips for freezing of gait – Novel solution for a disabling symptom.
Objective: To evaluate a novel method of visual cueing using patterned alternating-coloured strips made of electrical tape for freezing of gait. Background: Freezing of gait…Assessing akinesia domains during multitasking in Parkinson’s disease
Objective: To explore performance differences in single- versus dual-tasking conditions between healthy controls (HC) and Parkinson's disease (PD) patients. Background: Akinesia, comprising slowness (bradykinesia), reduction…Oculomotor changes in the premotor stage of LRRK2- G2019S associated Parkinson’s disease.
Objective: To analyse oculomotor differences among idiopathic PD patients (iPD), LRRK2-G2019S PD patients (LRRK2-G2019S PD), asymptomatic carriers of LRRK2-G2019S mutation (AsG2019S), and controls, evaluated by…New wearable technology for quantification of freezing of gait in school going adolescent with pediatric movement disorders
Objective: To study quantification of freezing of gait (FOG) and falls of patients data in school going adolescent with pediatric movement disorders by wearable device…
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