Analysis of the relationship between acoustic measures and VHI score
Objective: To examine whether there is a relationship between acoustic measurements extracted from audio recordings of sustained vowel /a/ of PWP and their VHI scores.…Comparison in the disability level according to WHODAS 2 between people living with Early and Late Onset Parkinson’s Disease
Objective: To compare disability levels according to WHODAS-2 between people living with EOPD and people living with LOPD. Background: Although Parkinson's disease (PD) is more…An Analysis of Subgroups of Multiple System Atrophy Patients from Ampreloxetine Phase 3 Trials
Objective: To present results in the subset of patients with multiple system atrophy (MSA) and relevant MSA subgroups from two ampreloxetine phase 3 trials for…Association of real-world wearable mobility measures with Parkinson’s disease severity and disease progression
Objective: To identify real-world mobility measures that are most reflective of PD severity and to assess their sensitivity to changes over time, as compared to…Training an APRN in movement disorders: lessons learned
Objective: To discuss the development and implementation of a training program of a neurology-naïve Advanced Practice Registered Nurse (APRN) into a small academic movement practice…Online recruitment and retention in the Parkinson’s Progression Markers Initiative (PPMI)
Objective: To describe participants and retention in the longitudinal PPMI Online cohort Background: The overall PPMI aim of biomarker identification to enable therapeutic development is…Understanding rehabilitation care utilization in Parkinson’s disease
Objective: The aim of our study was to examine experiences with rehabilitation services by people with Parkinson’s disease (PD) and their care partners (CP). Background:…Peripheral Synucleinopathy in Essential Tremor Plus Patients with Parkinsonian Features and Normal Dopamine Transporter Imaging
Objective: To describe results of skin biopsy for phosphorylated alpha-synuclein (P-SYN) in patients with essential tremor (ET) with parkinsonism. Background: Patients with longstanding ET may…Impaired Mitophagy and Mitochondrial-energetics in Parkinson’s disease: A Novel Therapeutic Strategy of Re-tasking Felodipine
Objective: This study aimed to validate impairment of mitochondrial energetics and mitophagy in PD and the action of felodipine in restoring altered Mitochondria-lysosome (Mito-Lyso) homeostasis.…Membrane-associated properties and ER stress alterations in LRRK2 I1371V patient iPSC derived neurons increase susceptibility to oxidative stress.
Objective: To evaluate the pathophysiology of the midbrain dopaminergic neurons (mDAN) derived from LRRK2 I1371V PD patient-iPSCs leading to susceptibility to oxidative stress. Background: Studies…
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