Custom-made Application Interface using Wacom® Tablet for Assessment of Writer’s Cramp
Objective: To evaluate a custom designed software platform to digitise handwriting data in writers cramp and normal controls. Background: Focal task specific dystonia occurring while…Evaluation of neuroprotective role of carvacrol via Nrf2-NLRP3 axis in rotenone induced PD mice model
Objective: To explore the antioxidant and anti-inflammatory role of Carvacrol via Nrf2-NLRP3 axis in rotenone induced PD mice model Background: NLRP3 inflammasome mediated neuroinflammation is…The long and short of contemporary parkinsonism survival: A 47-year clinicopathological study
Objective: We report a 47-year survival study of autopsy verified Parkinson syndrome (PS) and Parkinson’s disease (PD) cases. The objectives were: 1) to identify PS…Chinese herbal medicine treatment based on subgroup differentiation as adjunct therapy for Parkinson’s disease: interim analysis of a pilot add-on, randomized, controlled, pragmatic clinical trial
Objective: This interim data analysis preliminarily evaluated the feasibility and effectiveness of protocolized CHM on motor-related daily living of PD patients. Background: A Chinese national…KINETIC 2: An ongoing phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor
Objective: KINETIC 2 (NCT05173012) is an ongoing, phase 2b, randomized, double-blind, placebo-controlled, dose-response study that aims to evaluate the efficacy, safety, and tolerability of SAGE-324/BIIB124…Foslevodopa/foscarbidopa subcutaneous infusion shows similar infusion site reaction severity score across range of infusion rates in patients with Parkinson’s disease
Objective: Characterize the relationship between foslevodopa/foscarbidopa infusion rate and infusion site reaction (ISR) score in patients with Parkinson’s disease (PD) Background: As PD progresses, motor…Feasibility and efficacy of a multidisciplinary telemedicine intervention program to reduce falls and gait impairment in Parkinson’s disease (NCT04694443).
Objective: To evaluate the feasibility and effectiveness of a multidisciplinary telemedicine intervention program to reduce falls and to improve quality of life (QoL) in patients…Use of levodopa-carbidopa intestinal gel to treat a patient with multiple system atrophy (MSA)
Objective: To describe a case report on the use of Levodopa-carbidopa intestinal gel (LCIG) to treat non-motor symptoms in a patient with multiple system atrophy (MSA) Background: There is no…The crucial role of the visual system on the PISA syndrome in Parkinson’s disease
Objective: Patients with Parkinson's disease (PD) are significantly disturbed in their daily life when accompanied by the PISA syndrome (PS) of lateral bending. Background: We…Angiotensin II Type 1 (AT1) receptor antagonists as potential candidates for anxiety treatment in Parkinson’s Disease
Objective: The aim of this study was to explore the effects of Angiotensin II Type 1 receptor blockers (ARBs) and angiotensin-converting enzyme inhibitors (ACEIs) on…
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