Multi-stakeholder focus group study to develop recommendations of ways to improve treatment burden and capacity in Parkinson’s disease
Objective: To develop recommendations of ways to improve treatment burden and capacity in Parkinson’s disease (PD) Background: Our research has identified potentially modifiable factors of…Neurogenic Orthostatic Hypotension in Parkinson’s Disease: Is there a role for Locus Coeruleus Magnetic Resonance Imaging?
Objective: To test whether degeneration of the Locus Coeruleus (LC) is associated with Orthostatic Hypotension (OH) in Parkinson’s disease (PD).To test whether degeneration of the…Opicapone versus entacapone: Head-to-head comparison of Healthcare Resource Utilisation in COMT-I naïve People with Parkinson’s
Objective: In this retrospective cohort study, we assessed healthcare resource utilisation (HCRU) outcomes in People with Parkinson’s (PwP) naïve to Catechol-O-methyl transferase (COMT) inhibition via…Levodopa-induced dyskinesia and Huntington’s chorea: link to current motor control theories
Objective: Determine if there is a motor control hypothesis that could explain movement kinematics of Huntington’s disease (HD) chorea and Parkinson’s disease (PD) levodopa-induced dyskinesia…Istradefylline effect on Parkinson’s Disease Tremor, Motor symptoms and non-Motor symptoms.
Objective: Istradefylline is FDA approved for use in patients with PD treated with carbidopa-levodopa to reduce off time. GUH Movement Disorder Group has observed that…Progression of the Clinical Features of Progressive Supranuclear Palsy-Richardson Syndrome in Early and Advanced Stages
Objective: We sought to evaluate PSP-Richardson syndrome (PSP-RS) for uniformity of progression over nearly the entire disease course. Rather than comparing scores to the simple…Honey prevented MPTP-induced oxidative stress, neuroinflammation and gliosis in adult male Swiss mice.
Objective: To investigate the neuroprotective role of honey against oxidative stress and neuroinflammation induced by MPTP in adult male Swiss mice. Background: Oxidative stress and…Validation of the Patient Reported Outcomes in Parkinson’s Disease scale in outpatients
Objective: To validate PRO-PD in a random sample of outpatients with PD. Background: Successful treatment of Parkinson's disease (PD) requires symptom monitoring. Patient-Reported Outcomes in…MDS-UPDRS Part 3 cannot be summed with other parts of the MDS-UPDRS: a clinimetric evaluation
Objective: To establish whether summing scores of Movement Disorder Society– sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) Part 3 (Motor Examination) with…An IMU- based Objective Quantification Method for Bradykinesia Evaluation in Parkinson’s disease
Objective: Proposing an inertial measurement unit (IMU)-based objective quantification method for bradykinesia evaluation in Parkinson’s disease (PD) using MDS UPDRS III. Background: MDS-UPDRS III rating…
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