Regional brain volume and cognitive alterations in Huntington’s Disease Patients
Objective: To investigate i) HD patterns of cortical and subcortical atrophies ii) associations between atrophy and clinical, motor and cognitive features. Background: Huntington’s disease (HD)…Development of an Item Bank for Assessing Psychosis in Parkinson’s Disease: A Systematic Review
Objective: This study aimed to develop an item bank for assessing psychosis in Parkinson's disease (PD). Background: Psychosis is a common and debilitating symptom in…Mitochondrial DNA copy number is associated with the severity of motor symptoms and dementia in Parkinson’s disease
Objective: We aimed to investigate the diagnostic and prognostic role of blood mitochondrial DNA copy number (mtDNA-CN) measured by whole genome sequencing (WGS) in relation…Exploring the effects of torsinA dysfunction in an iPSC-derived neuronal model of TOR1A dystonia
Objective: To investigate phenotypic differences between iPSC-differentiated cortical neurons derived from patients with TOR1A dystonia compared to healthy controls. Background: Primary generalised dystonia is most…Online education to promote compensation strategies for gait impairments in underserved Parkinson populations
Objective: Here, we explore the potential health benefits of using an online educational platform about compensation strategies for gait impairment in Parkinson’s disease (PD), in…How does a diagnosis of Dementia with Parkinson’s influence future care provision?
Objective: To describe the trajectory of Parkinson’s after the onset of dementia including setting of care, frailty levels and mortality rate. Background: Cardiff and Vale…Trial site factor in Parkinson’s disease (PD) diary non-compliance
Objective: In this analysis, we wanted to explore if PD diary non-compliance is distributed randomly in the dataset or if it has a tendency to…Epidemiology of late-onset Parkinson’s disease in least-developed to Upper Middle-Income Countries: A Systematic Review and Meta-analysis
Objective: To conduct a meta-analysis of the epidemiological studies of Parkinson's disease (PD) performed in populations from least-developed to upper-middle-income countries. Background: While several epidemiology…Association between Parkinson’s Disease and Atrial Fibrillation: A Literature Review
Objective: Our literature review aims to summarize what has been reported in the literature with the next steps of looking at Kaiser Permanente (KP) to…Neurofilament light chain, tau-PET and microglia-PET predict clinical progression in amyloid-negative corticobasal syndrome
Objective: A head-to-head comparison of neuroimaging (tau-PET, microglia-PET, structural MRI) and plasma biomarker Neurofilament light chain (NfL) as prognostic tools for longitudinal clinical trajectories in…
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