Measuring the heterogeneity of disease progression in Parkinson’s disease with multimodal clinical milestones over 10 years in the DeNoPa cohort
Objective: To provide a reference of individual Parkinson’s disease (PD) progression by assessing multimodal milestones over 10 years (y) in patients of the DeNoPa cohort.…Premenstrual worsening of UPDRS motor scale in women affected by Parkinson’s Disease
Objective: The role of estrogen in dopaminergic pathways and the premenstrual worsening of parkinsonian symptoms. Background: Female sex hormones, during the menstrual cycle, could influence…Association of sex with health-related quality of life in adults with chronic tic disorders
Objective: To investigate if there was an association of sex with health-related quality of life (HR-QOL) and psychiatric comorbidities in adults with Tourette syndrome (TS)…Enrollment phase sensing data from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease (ADAPT-PD) clinical trial
Objective: To describe enrollment sensing data from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease (ADAPT-PD) trial (NCT04547712). Background: Local field potential (LFP)…Subtyping Parkinson’s disease: Quality of life changes after subthalamic stimulation depend on nonmotor and motor symptoms
Objective: To investigate if patients with Parkinson’s disease (PD) undergoing subthalamic stimulation (STN-DBS) can be clustered in different subtypes based on demographic, motor and non-motor…Reliability of brainsense technology as compared to SoC in STN DBS programming
Objective: We aimed to study coincidence between the contact selected at programming session by experienced neurologists at 6months follow up after bilateral STN DBS (considered…Neuroimaging correlates of postural instability in motor subtypes of Parkinson’s disease
Objective: In this study, we aimed to identify the brain structures associated with postural instability (PI) in Parkinson’s disease (PD) subtypes using different MRI approaches. Background:…Bilateral subthalamic nucleus deep brain stimulation in Parkinson’s disease: preoperative predictors of speech worsening
Objective: To find preoperative predictive factors of short-term postoperative speech worsening in a large cohort of consecutive PD patients treated with bilateral STN-DBS. Background: Subthalamic…A novel truncating variant in UBAP1 gene causing hereditary spastic paraplegia type 80
Objective: To describe a novel truncating variant in UBAP1 gene in a first Malay population, and expand the genotype and phenotype. Background: Hereditary Spastic paraplegia…A retrospective comparison of functional and quality of life outcomes in DBS patients implanted via awake or asleep surgery: the Rush University Medical Center experience
Objective: We retrospectively compared quality of life and functional status metrics to assess differences among patients who underwent implantation of Deep Brain Stimulation (DBS) for…
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