Autosomal Recessive GTPCH Deficiency: Redefining the Phenotypic Spectrum and Outcome
Objective: To describe the clinical phenotype of autosomal recessive GTP cyclohydrolase deficiency (ARGTPCHD), its genetic and metabolic correlates, and their possible predictive value through a…Ionic Plasticity of Midbrain GABAergic Synapses in PD Models
Objective: To validate that enhancing potassium-chloride cotransporter activity would restore inhibition and normal function in parkinsonian Substantia nigra reticulata (SNr) and participate to Parkinson’s disease (PD) symptom alleviation. Background: The SNr is an output nucleus…Oscillatory network mapping of deep brain stimulation outcomes in Parkinson’s disease
Objective: Use combined local field potential (LFP) and Magnetoencephalography (MEG) recordings to map whole-cortex oscillatory connectivity and estimate deep brain stimulation (DBS) outcome. Background: Subthalamic…Temporal coordination of head and trunk during 360-degree turning in Parkinson’s Disease
Objective: The purpose of this study is to investigate different strategies of temporal coordination of the head and trunk in people with Parkinson's disease(PD) while…Impact of sub-acute MPTP exposure on the cerebellum in adult male Balb/c mice
Objective: The objective of the study was to investigate the effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration on the cerebellum of adult male Balb/c mice Background: Parkinson’s…Putaminal dopamine modulates movement motivation in Parkinson’s disease
Objective: To investigate the quantitative effect of dopamine depletion on the motivation of motor effort in Parkinson’s disease. Background: The relative inability to produce effortful…www.PregSpark.com, introducing the International PregnancieS and Parkinson’s Registry
Objective: To introduce the International PregnancieS and Parkinson’s Registry (www.PregSpark.com). Background: Pregnancy in Parkinson’s disease (PD) is rare, but with PD being the fastest growing…Developing composite measures that track physical activity change in people with early-stage Parkinson’s disease using machine learning and wearable sensors
Objective: To describe an approach using machine learning (ML) to develop composite digital measures that capture changes in physical activity in people with early-stage Parkinson’s…Education Levels on Diagnostic Delay Phase and Initial Symptom Perception Among Hispanic Patients with Parkinson’s Disease: A Cross-Sectional Study
Objective: Determine the relationship between education levels and the diagnostic delay phase, along with the age of symptom perception, in Hispanic patients with Parkinson's disease…Selective subthalamic DBS improved non-motor disorders without affecting weight gain in parkinsonism
Objective: Evaluate the impact of subthalamic nucleus deep brain stimulation (STN-DBS) on weight gain in Parkinsonian rats: The primary objective would be to determine whether…
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