Levodopa response is an inadequate and often biased correlate of STN-DBS outcomes
Objective: To investigate the reliability of the relationship between levodopa response and subthalamic nucleus (STN) DBS outcomes in Parkinson disease (PD). Background: Levodopa response (LR)…Clinically implemented sensing-based initial programming of deep brain stimulation for Parkinson’s disease: a retrospective study
Objective: We aimed to assess the feasibility and performance of clinically implemented sensing-based initial deep brain stimulation (DBS) programming for Parkinson’s disease (PD). Background: Initial…Artificial Intelligence and Visual Analysis of Movements in Parkinson’s Disease
Objective: To evaluate the use of artificial intelligence in the analysis and classification of movements in Parkinson's disease. Background: Artificial intelligence (AI) is a powerful…Reliability of real-world walking activity and gait assessment in people with Parkinson’s disease – how many hours and days are needed?
Objective: To define i) the minimally required daily wear time during waking hours that constitutes a valid measurement of walking using digital mobility outcomes (DMOs)…Use of social media and health information technology among caregivers of Alzheimer’s disease and other neurological conditions: Secondary analysis of the 2022 Health Information National Trend (HINTS) Survey
Objective: This study aims to evaluate the pattern of health information seeking from social media and other health technology tools among caregivers for individuals with…Measuring Motor Improvement with a Wearable Device in a Parkinson Disease Patient undergoing Subcutaneous Levodopa Carbidopa Infusion
Objective: To assess the feasibility of a wearable device for objective quantification of motor improvement in Parkinson's Disease (PD) patients undergoing a therapy from oral…Motor Onset of Parkinson’s disease: the proximal limbs are first
Objective: To determine if proximal body parts are more affected than distal body parts at the clinical onset of Parkinson’s disease (PD). Background: Motor features…Mixed Cerebellar Ataxia in a Patient with a Novel FAT2 Gene Variant Associated with SCA45
Objective: We describe a patient with late-onset ataxia, cognitive impairment, and parkinsonism with a novel missense variant in FAT2, a gene implicated in spinocerebellar ataxia…Spinocerebellar Ataxia Type 4: a Novel Polyglycine Disease caused by GGC Repeat Expansion in ZFHX3.
Objective: Identification of the mutation causing SCA4. Background: SCA4 is an autosomal dominant disease, originally described in a large Utah pedigree, characterized by sensory and…CAPRIN1 defect: a new severe neurodegenerative disorder with childhood dementia, myoclonus-ataxia, and sensorimotor neuropathy
Objective: To present the case of a patient with a severe neurodegenerative disorder with onset in pediatric age carrying a pathogenic variant in CAPRIN1 gene…
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