Is fatigue a rate limiting factor for achieving motor learning and functional gains in people with spinocerebellar ataxia? (PRIME-Ataxia RCT)
Objective: Determine the feasibility and preliminary efficacy of an 8-week telehealth intervention of high intensity aerobic exercise prior to balance training (HIBT) compared to low…Masticatory function evaluation methods in movement disorders
Objective: To characterize masticatory function in individuals with Parkinson's Disease (PD) and Spinocerebellar Ataxia (SCA3) regarding the orofacial myofunctional condition (OMES-E), the masticatory performance and…The neural contributions to fear of falling avoidance behavior in Parkinson’s disease: preliminary evidence from a mobile neuroimaging paradigm
Objective: The purpose of this study was to determine the relationship between fear of falling avoidance behavior (FFAB) and cortical hemodynamic response during dual-task (DT)…The Impact of Apathy and Impulsivity on Caregivers in Atypical Parkinsonian Syndromes
Objective: This study aims to investigate the impact of apathy and impulsivity on the quality of life and burden for carergivers of people with Atypical…Parkinson’s Disease (PD) and predictors of Driving Cessation: Results from a 6-year Longitudinal Study and a systematic review of the literature
Objective: We sought to identify predictors of driving cessation among PD patients. Background: Motor and cognitive impairment of PD patients interfere with their driving ability.…Experiencing Life with Tourette Syndrome: The Invisible Effects of Tics
Objective: To evaluate how individuals with Tourette Syndrome experience stigma. Background: Persistent Tic Disorders (PTD), including Tourette Syndrome (TS), are neurodevelopmental disabilities characterized by multiple…Safety and Efficacy of Vatiquinone Treatment in Friedreich Ataxia Patients from MOVE-FA: a Phase 3, Double-blind, Placebo-controlled Trial
Objective: Describe the results of vatiquinone from MOVE-FA (NCT04577352), the 72-week placebo-controlled phase 3 study of patients with Friedreich Ataxia (FA). Background: FA, the most…Nocturnal Use of Add-On Medications for Parkinson’s Disease: Post Hoc Analysis of the COSMOS Study
Objective: To assess nighttime use of add-on medications for Parkinson’s disease (PD) in a post hoc analysis of the COSMOS (COmedication Study assessing Mono- and…Subgroup Analyses of a Phase 3 Randomized Study of Levodopa/Carbidopa Infusion (ND0612) for Parkinson’s Patients
Objective: Evaluate efficacy and safety outcomes for different patient subgroups categorized according to their baseline characteristics from a Phase 3 study of ND0612. Background: Primary…REGENERATE-PD: A Phase 2, Randomized, Double-Blind, Surgery-Controlled Study of GDNF Gene Therapy (AAV2-GDNF; AB-1005) for Moderate Stage Parkinson’s Disease
Objective: To present the REGENERATE-PD study design: a phase 2, randomized, double-blind, surgery-controlled trial assessing efficacy and safety of intraputaminal adeno-associated virus serotype 2 containing…
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