Association Between Clinical Progression in Multiple System Atrophy and Brain Volume Changes Evaluated via Deep Learning Segmentation
Objective: Assess brain volume changes in patients with multiple system atrophy (MSA) over one year. Background: Identifying disease progression biomarkers is crucial for advancing MSA…Nigral Neuroinflammation and Dopaminergic Neurons in PD, MSA and PSP: A Comparative Clinicopathological Study
Objective: To investigate nigral neuroinflammatory markers and dopaminergic neuron counts in parkinsonian disorders, comparing their profiles across conditions. Background: In degenerative parkinsonian disorders, the primary…Regional tau burden patterns and their associations with clinical severity in progressive supranuclear palsy (PSP)-Richardson’s syndrome and PSP- predominant parkinsonism: a prospective cohort study
Objective: To explore whether PSP-RS) and PSP-P have different regional tau burden distributions in the brain and whether these distributions are related to motor and…Ethnic Diversity and Symptomatology in Parkinson’s Disease with a Focus on Falls and Vertical Gaze Palsy
Objective: The objective of this study was to explore atypical features in the clinical phenotype of people with Parkinson’s disease (PwP) enrolled in the East…Plasma pTau181 and pTau217 Detect Amyloid Co-pathology and Have Specific Cut-offs in Lewy Body Disease
Objective: We assess: 1) if the diagnostic accuracy of plasma pTau181 differs from pTau217 in detecting amyloidosis (Aβ) in people with Lewy body disease (LBD)…MDS Clinical Supportive Criteria for Parkinson’s Disease are Associated with α-Synuclein Seed Amplification Assay Status
Objective: To assess the association between α-synuclein seed amplification assay (α-synuclein SAA) status with the supportive criteria of the MDS Clinical Diagnostic Criteria for Parkinson’s…Association Between DPP-4 Inhibitors Use and Risk of Dementia: A Meta-analysis Using Real-world Data
Objective: To investigate the potential association between the use of DPP-4 inhibitors and the risk of dementia, utilizing real-world data from diverse sources. Background: Evidence…Quantitative Assessment of X-linked Dystonia-Parkinsonism Using Wearable Sensing Technology
Objective: To create a quantitative, objective framework for assessing combined dystonia parkinsonism using kinematic data from wearable sensors combined with machine learning (ML), enabling clinician-independent…The Impact of Camp Lejeune Toxins on the Development of Parkinsonisms and Movement Disorders
Objective: To further characterize movement disorders seen in Veterans exposed to toxins at Camp Lejeune military base. Background: Recent reports reveal that water in the…Comparison of Composite Method Calculations for Monitoring Disease Progression in Early Parkinson’s Disease
Objective: Objective: To evaluate the influence of composite scoring methodologies using digital measures of gait, tremor, and bradykinesia to monitor disease progression over one year…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.