Parkinsonism due to Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) Responsive to Carbidopa/Levodopa
Objective: To describe a case of Parkinsonism due to ALSP which is responsive to carbidopa/levodopa Background: Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP)…The impact of cognitive impairment and Alzheimer’s disease neuropathological changes on gait and falls in Parkinson’s disease
Objective: To investigate the association between clinical markers of cognitive impairment, severity, and distribution of Alzheimer's disease neuropathological changes (ADNC) with gait difficulties, freezing of…Creation and Performance of a Cognitive Summary Score in de novo Parkinson’s Disease: Results from the PPMI Study
Objective: To determine if a cognitive summary score (CSS) is sensitive in detecting early cognitive deficits in de novo Parkinson’s disease (PD). Background: Cognitive impairment…Characterisation and longitudinal significance of subjective cognitive decline in GBA and LRRK2 Parkinson’s disease
Objective: To investigate the clinical characteristics and predictive value associated with subjective cognitive decline (SCD) in people with Parkinson’s disease (PD) carrying pathogenic GBA or…Semantic Memory in Parkinson’s Disease: Linguistic Features and Neural Correlates
Objective: This study aims to characterize behavioral and neural correlates of semantic processing in Parkinson’s disease (PD). Background: Cognitive studies on PD reveal abnormalities during…Integrating Non-Motor Symptoms and Gender Variability in Machine Learning for Early Parkinson’s Disease Detection
Objective: Our study aimed to develop a machine learning (ML) model for the early detection of Parkinson's disease (PD), utilizing non-motor symptoms (NMS) and DNA…Autonomic Dysfunction in Parkinson’s Disease Link with disease severity and other non-motor signs
Objective: Clarify the relationship between autonomic dysfunction, disease severity and NMS in PD patients. Background: Parkinson’s disease (PD) is characterized by a combination of motor…Validation of the International Parkinson and Movement Disorder Society – Non-Motor Symptoms – Questionnaire (MDS-NMS-Q)
Objective: To validate the self-completed version of the International Movement Disorder Society – Non-Motor Rating Scale (MDS-NMS)1, named the MDS-NMS – Questionnaire (MDS-NMS-Q). Background: The…Exploring Supervised and Real-World Mobility in People with Parkinson’s Disease with and without Nocturnal Hypokinesia
Objective: To evaluate supervised and real-world mobility in people with Parkinson’s disease (PwPD) with and without nocturnal hypokinesia (NH). Background: Mobility impairment and NH are…Beyond constipation: gastrointestinal phenomena in Parkinson’s disease
Objective: To describe the prevalence of gastrointestinal manifestations in patients with Parkinson's disease in a Brazilian movement disorders outpatient clinic and evaluate their associated factors…
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