Disease Progression in Patients with PLA2G6-related Parkinsonism: A Longitudinal Study
Objective: To investigate disease progression of PLA2G6-related parkinsonism in a longitudinal study. Background: There is a paucity of follow-up studies on disease progression in PLA2G6-related…Genetic Modifiers of Age at Onset for Parkinson’s Disease in Chinese Population
Objective: This study aimed to identify novel genetic modifiers of age at onset (AAO) for Parkinson’s disease (PD) including common variants and rare variants using…Common Genetic Variation Associated with Parkinson’s Disease Biological Measures
Objective: To identify common genetic variants associated with biological measures that have been implicated in Parkinson’s disease and related synucleinopathies. Background: Alpha synucleinopathies, mainly including…Determining and Leveraging Local Ancestry to Assess Individual-Level Risk: from the Global Parkinson’s Genetics Program
Objective: We develop a scalable pipeline leveraging existing tools to determine local ancestry for all individuals in the Global Parkinson’s Genetics Program (GP2), aiming to…Expanding Phenotype of LRRK2 G2019S Mutation: Case Description of Two Sisters Showing Peculiar Phenomenological Traits
Objective: The aim of this case report is to describe and expand LRRK2 phenomenology, including clinical presentation and disease course. Background: LRRK2 is the most…Real-life experience of switching from D-penicillamine to trientine tetrahydrochloride – a nationwide registry study
Objective: Our aim was to assess the efficacy and safety of trientine tetrahydrochloride (TETA4HCL) in a cohort of neurological Wilson's disease (WD) patients transitioned from…Movement Disorders in De Novo Hyperglycemic Crisis: Insights from a Clinical Case Series
Objective: To investigate the clinical spectrum and implications of movement disorders (MD) in patients presenting with de novo hyperglycemic crisis (DNHC). Background: DNHC, characterized by…Investigation of the Beta Oscillations of Local Field Potential in the Subthalamic Nucleus of the Parkinsonian Minipig Model
Objective: To investigate the features of beta oscillations of the subthalamic nucleus (STN) in the Parkinsonian minipig model. Background: Deep brain stimulation (DBS) is an…Exploring the neural correlates of impulsivity and impulsive compulsive behaviors in Parkinson’s disease
Objective: To explore the subcortical neural correlates of impulse control and related behavioral disorders (ICBD) and trait impulsivity in a chronic and naturalistic setting in…Longitudinal Studies of LFP Activities During Acute and Chronic DBS Stimulation in PD Patients
Objective: This study investigates the changes in local field potential (LFP) during acute and chronic deep brain stimulation (DBS) in patients with Parkinson's disease (PD)…
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