Quantification of Neuroinflammation and White Matter Injury in Parkinson Disease Using Diffusion Basis Spectrum Imaging
Objective: To investigate differences in white matter (WM) using Diffusion Basis Spectrum Imaging (DBSI) between participants with Parkinson’s disease (PD) and controls and to examine…Comparing 18F-AV133 VMAT2 PET and DATscan as Markers of Parkinson’s Disease Severity and Progression
Objective: Compare VMAT2 PET signal with DATscan at baseline and over time, and evaluate their correlations with MDS-UPDRS III. Background: DATscan is a Parkinson’s disease…The Contribution of APOE4 Genotype on Structural MRI in Parkinson’s Disease: A Study from the PPMI Cohort
Objective: To assess the contribution of Apolipoprotein E4 (APOE4) in Parkinson’s Disease (PD)-related cognitive impairment by analyzing its impact on Gray Matter Volume (GMV). Background:…Effects of striatal dopamine depletion and altered brain metabolism on Parkinson’s disease
Objective: To investigate the relationship between striatal dopamine depletion, altered brain metabolism, motor deficits, and cognitive dysfunction in Parkinson’s disease (PD) Background: PD shows degeneration…Examination of how DaTscan Impacts Diagnosis in Parkinsonian Patients with and without Dopamine Receptor Blocking Agent Exposure
Objective: To determine whether Dopamine transporter imaging impacts diagnosis in parkinsonian patients Background: Dopamine transporter imaging (DaTscan) is a diagnostic tool used to assess loss…Alterations in neural processes of cognitive control in asymptomatic heterozygous mutation carriers in the Parkin gene
Objective: Investigating heterozygous Parkin gene (PRKN) mutation carriers to evaluate the potential association of this mutation with an alteration of cognitive control processes. Background: Recessively…Protocol for Cerebellar Deep Brain Stimulation in Children and Young Adults with Dyskinetic Cerebral Palsy: Combined N-of-1 trials to Assess Safety and Efficacy
Objective: This study seeks to alleviate severe movement and tone disorders in cerebral palsy (CP) through chronic neuromodulation using deep brain stimulation (DBS), targeting motor…Raynaud’s Phenomenon and Diaphoresis During Initial Programming of Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease: A Case Report
Objective: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for motor symptoms in advanced Parkinson's disease (PD). However, autonomic side…Is Neuropsychological Evaluation Needed to Assess DBS Candidacy in Essential Tremor?
Objective: In this study we examined frequency of cognitive and psychiatric disorders identified during neuropsychological evaluation for Deep Brain Stimulation (DBS) in patients with Essential…Feasibility and added value of sensing feature in patients with chronic STN DBS for Parkinson’s disease
Objective: To test the feasibility and usefulness of sensing features in patients undergoing replacement of their implantable pulse generator (IPG). Background: People with Parkinson’s disease…
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