Decline in Motor Function and Cognitive Abilities in GBA PD Compared to Idiopathic PD (iPD)
Objective: To compare disease progression events between GBA PD and iPD using the Parkinson’s Progression Markers Initiative (PPMI) database Background: GBA PD patients exhibit more…Impact of parkinson’s disease on work disability: a cross-sectional study
Objective: To evaluate the impact of Parkinson’s disease (PD) on work disability and identify clinical and demographic factors associated with occupational impairment. Additionally, this study…Elucidating Tau and Alpha-synuclein Co-pathology in RAB39b X-linked Parkinson’s Disease.
Objective: Elucidate the mechanisms underlying pathogenesis of X-linked Parkinson’s disease (PD) due to the RAB39B p.G192R mutation. Background: RAB39B p.G192R causes X-linked PD with decreased…The Impact of Microgravity and Herpes Simplex Virus 1 on Parkinson’s Neurodegeneration and HERV Expression
Objective: The present abstract aims to investigate the impact of viral infections and microgravity exposure in the context of Parkinson’s disease (PD). Background: PD is…Utilising Beta Power in Local Networks to Predict Freezing of Gait Events in Parkinson’s Disease
Objective: Our study examined brain network changes during the transition to Freezing of Gait (FOG) versus voluntary stopping. Identifying specific neural alterations may help establish…Fatty Acid Metabolic Reprogramming Regulates Glial-Epithelial Axis via Nur77 Palmitoylation in Intestinal Dysfunction in Parkinson’s Disease
Objective: This study aims to elucidate the regulatory role of stearoyl-CoA desaturase 1 (SCD1) in Parkinson’s disease (PD)-associated intestinal dysfunction, focusing on its mechanism in…Identification of Distinctive Iron Deposition Pattern in Subcortical Nuclei of Parkinson’s Disease using Radiomics: A 7T Susceptibility-Weighted Imaging Study
Objective: To develop the optimal radiomics signature of distinctive subcortical nuclei iron deposition pattern for diagnosis and differential diagnosis of Parkinson’s disease (PD) at 7T susceptibility-weighted imaging (SWI).…Dopaminergic and Synaptic Alterations in SWEDD: Insights from [¹⁸F] FE-PE2I and [¹¹C] UCB-J PET Imaging
Objective: To investigate dopaminergic and synaptic density in SWEDD patients compared to idiopathic Parkinson’s disease (IPD) and healthy controls (HCs). Background: Scans Without Evidence of…A novel potential imaging biomarker for Parkinson’s disease: Optical Coherence Tomography.
Objective: This observational cross-sectional study aims to explore the thickness of retinal layers in patients within the PD continuum, patients with isolated REM Sleep Behavior…The regulatory variant c.–253C>T of the DNAJC13 gene as a causal factor for Parkinson’s disease in a patient with early-onset
Objective: This work aims to investigate the role of regulatory regions in Parkinson’s disease (PD) genes, which may help explain part of the missing heritability.…
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