The Role of Physiotherapy in Demystifying Parkinson’s Disease and Movement Disorders in Uganda.
Objective: To evaluate the effectiveness of physiotherapy interventions in improving motor function, quality of life, and stigma reduction for individuals with Parkinson’s disease in Uganda.…Apathy and Risk of Parkinson’s Disease: A Population-Based Cohort Study
Objective: This study investigated the association between apathy and the risk of incident Parkinson's disease (PD) in community-dwelling adults. Background: Apathy is a core neuropsychiatric…A Biomarker-Directed Approach to the Early Diagnosis of Parkinson’s Disease Using Artificial Intelligence and Machine Learning
Objective: The main purpose of this study was to assess how AI and ML methods integrate multiple biomarkers for diagnosing Parkinson’s Disease (PD) to improve…Cell-type specific bidirectional modulation of STN neurons rescue Parkinsonian motor symptom.
Objective: This study aimed to identify the specific STN cell type and circuit responsible for alleviating parkinsonian motor symptoms through targeted neural modulation. Background: The…Improving Motor and Non-motor Symptoms in Parkinson’s Disease: A combined Pharmaceutical and Digital Approach Targeting Parallel Neural Circuits
Objective: We aimed to demonstrate the parallel neural mechanisms underlying the effects of combining standard levodopa treatment with the DopApp digital intervention on motor and…Subthalamic β frequency oscillatory activity is modulated by self-paced wrist movement
Objective: To explore whether subthalamic β oscillatory neurons are associated with the initiation of voluntary movement in patients with Parkinson’s disease (PD). Background: The basal…Striatal Dysfunction in Parkinson’s Disease Progression: A 18F-9-fluoropropyl-(+)-dihydrotetrabenazine(18F-AV133) PET Study
Objective: To investigate the patterns of striatal 18F-AV133 uptake in relation to disease progression across different stages of PD and to examine its relationship with…The Associations between Cognitive Reserve Proxies, Multimodal MRI Brain Measures and Cognition, Motor Function and Mood in Parkinson’s Disease
Objective: This study aimed to use multimodal MRI to explore the relative importance of cognitive reserve (CR) proxies, compared to CR- and Parkinson’s disease (PD)-related…Brain hemodynamic responses to a motor control paradigm in younger and older adults, and people with Parkinson’s Disease: An fNIRS mediated feasibility study.
Objective: This study aims to investigate the use of fNIRS in measuring the hemodynamic response of the brain during motor control tasks of increasing complexity…Assessing Genome-wide Genetic Risk for Parkinson’s Disease Age at Onset in European Sub-Populations: from the Global Parkinson’s Genetics Program
Objective: To identify the genetic determinants of Parkinson’s disease (PD) age at onset (AAO) within and across genetically determined European ancestries (European, Ashkenazi Jewish, Finnish,…
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