1H-NMR and UPLC/MS Metabolomics Identify Disrupted Homeostasis of Energy, Amino Acids, and Glutathione Metabolism as Serum Signatures in Parkinson’s Disease Patients
Objective: We sought to identify a signature distinctive of Parkinson’s disease (PD) through two independent metabolomics approaches. Background: A recent meta-analysis showed a considerable inconsistency…Stratification study of alpha-synucleinopathy by body fluid biomarkers
Objective: This study aims to stratify patients with Parkinson's disease (PD) based on clinical features and several disease-associated biomarkers by analyzing the relationship between biomarkers,…Determinants of Cognitive Progression in Parkinson’s Disease: A Machine Learning Approach
Objective: To identify clinical and sociodemographic factors associated with cognitive decline (CD) in PD using a Random Forests model, classifying people with PD (PwP) into…Characteristics of apathy in clinical forms of Parkinson’s disease
Objective: To study the severity of PD in clinical forms. Background: Apathy is one of the most common symptoms in Parkinson's disease (PD), which can…Deep Brain Stimulation Increases Motivation to Obtain Larger Rewards in Parkinson’s Disease
Objective: To assess the effects of deep brain stimulation (DBS) on effort and reward processing for self-benefitting and prosocial behavior in people with Parkinson’s Disease…Comparison of 3 Tests for Subjective Cognitive Complaints in Early Parkinson’s Disease
Objective: To compare 3 scales which have been used in literature to determine subjective cognitive complaints (SCC) in Parkinson’s disease (PD) and explore their relationship…Pilot Feasibility Data using Augmented Reality and Machine Learning-Based Digital Cognitive Assessment in Parkinson’s disease
Objective: To assess the feasibility of using a novel cognitive and functional digital biomarker assessment, the Altoida NeuroMarker platform, to evaluate the presence of MCI…Quality of Life and Depression in Patients with and without Idiopathic Parkinson’s Disease without Dementia.
Objective: To identify the impact of depression on QoL in a group of patients with IPDWD. Background: The Quality of Life (QoL) in patients with…Life Course Sleep Duration Trajectories and Risk and Age at Onset of Parkinson’s Disease
Objective: To characterize life course sleep duration trajectories and examine their associations with PD risk and age at onset (AAO). Background: Sleep disturbances could be…Subthalamic versus Pallidal Temporal Interference Stimulation in Parkinson’s Disease: A Pilot Study
Objective: To investigate whether transcranial temporal interference stimulation (tTIS) targeting different deep brain regions produces symptom-specific improvements consistent with established deep brain stimulation (DBS) outcomes…
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