Detection and classification of Parkinson’s disease from neuroimaging modalities using machine learning and artificial intelligence: a systematic review
Objective: This systematic review evaluates performance of machine learning (ML) and artificial intelligence (AI) techniques applied to neuroimaging modalities in differentiating Parkinson’s disease (PD) patients…Striatal dopamine- and basal forebrain cholinergic-dependent brain metabolism and cognition in Parkinson’s disease
Objective: To explore the interrelation of striatal dopamine, cholinergic basal forebrain volume, brain metabolism, and cognition in PD. Background: Parkinson’s disease (PD) involves multiple neurotransmitter…Cerebral Glucose Metabolic Features of GBA-Parkinson’s Disease as a window into cognitive impairment
Objective: to investigate cerebral glucose metabolism via fluorodeoxyglucose positron emission tomography (FDG-PET) and its correlation to clinical features in Parkinson’s disease (PD) patients with GBA1…A Multi-Transcriptional Risk Score Approach to Parkinson’s Disease Prediction
Objective: To improve the prediction of Parkinson’s disease (PD) by examining aggregate profiles of gene expression in the form of transcriptional risk scores (TRS). Background:…Investigating the Global Genetic Spectrum of Monogenic Parkinson’s Disease and Parkinsonism
Objective: To investigate known pathogenic and risk variants linked to Parkinson’s disease (PD) at a global, multi-ancestry scale. Background: Genetic forms of PD have been…Mutations of the VPS13A gene in a patient with Early-Onset Parkinson’s Disease: A case report.
Objective: To describe the case of a patient with early-onset Parkinson's Disease (PD) with variants of the VPS13A gene. Background: The vacuolar protein sorting 13A…Examining the Gut Microbiome in Parkinson Patients with GBA Mutations
Objective: Gut dysbiosis is implicated in Parkinson disease (PD) pathogenesis, but less is known about the interaction of PD associated gene variants and gut microbiota.…Advancing Global Training and Capacity Building in Parkinson’s Genetics through GP2
Objective: To promote and facilitate learning by providing resources and expertise to address the training needs of the Global Parkinson’s Genetics Program (GP2; www.gp2.org) and…Rare Variants, Copy Number Variations, and Heritability Estimates in a Pilot Cohort of Egyptians with Parkinson’s Disease
Objective: To explore the genetic architecture of Parkinson's disease (PD) in Egypt, addressing the underrepresentation of this population in PD genetics research. Background: Genetic studies…Predictors of Cognitive Impairments and Mood Disorders after Subthalamic Deep Brain Stimulation in Patients with Parkinson’s Disease
Objective: We aimed to determine the predictors of cognitive decline and mood disorders after STN-DBS in PD. Background: Cognitive impairment and mood disorders are the…
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